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Journal of Inherited Metabolic Disease|October 25, 2013
Valproyl-CoA inhibits the activity of ATP- and GTP-dependent succinate:CoA ligasesPaula B M Luís, Jos Ruiter, Lodewijk IJlst, et al.Journal of Inherited Metabolic Disease|December 23, 2011
Inhibition of 3-methylcrotonyl-CoA carboxylase explains the increased excretion of 3-hydroxyisovaleric acid in valproate-treated patientsPaula B M Luís, Jos P Ruiter, Lodewijk IJlst, et al.FEBS Letters|September 9, 2008
Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranesCátia C P Aires, Graça Soveral, Paula B M Luís, et al.Biochimica Et Biophysica Acta|August 21, 2007
Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylationPaula B M Luís, Jos P N Ruiter, Cátia C P Aires, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 25, 2011
Role of isovaleryl-CoA dehydrogenase and short branched-chain acyl-CoA dehydrogenase in the metabolism of valproic acid: implications for the branched-chain amino acid oxidation pathwayPaula B M Luís, Jos P N Ruiter, Lodewijk Ijlst, et al.Biochemical Pharmacology|August 17, 2011
Valproic acid utilizes the isoleucine breakdown pathway for its complete β-oxidationPaula B M Luís, Jos P Ruiter, Rob Ofman, et al.Biochimica Et Biophysica Acta|February 27, 2007
Studies on the extra-mitochondrial CoA -ester formation of valproic and Delta4 -valproic acidsCátia C P Aires, Jos P N Ruiter, Paula B M Luís, et al.Pageof 1