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Nature|February 3, 2015
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repairRaphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, et al.Molecular Cell|May 15, 2018
Polε Instability Drives Replication Stress, Abnormal Development, and TumorigenesisRoberto Bellelli, Valerie Borel, Clare Logan, et al.Nature Communications|April 20, 2023
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathologyOliver J Ziff, Jacob Neeves, Jamie Mitchell, et al.Nature Communications|June 21, 2022
Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cellsClara Lopes Novo, Emily V Wong, Colin Hockings, et al.Cell Reports|January 26, 2023
Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathwaysJoost Schimmel, Núria Muñoz-Subirana, Hanneke Kool, et al.Molecular Cell|April 19, 2022
H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJRachel Bayley, Valerie Borel, Rhiannon J Moss, et al.Nature|September 6, 2013
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesisCarrie A Adelman, Rafal L Lolo, Nicolai J Birkbak, et al.Molecular Cell|August 27, 2013
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathiesHyo Jei Claudia Choi, Jia-Ren Lin, Jean-Baptiste Vannier, et al.Science (New York, N.Y.)|April 9, 2021
Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitorsKasper Fugger, Ilirjana Bajrami, Mariana Silva Dos Santos, et al.Molecular Cell|October 6, 2023
Negative DNA supercoiling induces genome-wide Cas9 off-target activityMatthew D Newton, Marialucrezia Losito, Quentin M Smith, et al.Pageof 15