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Drug Discovery Today
|
November 27, 2015
The ELF Honest Data Broker: informatics enabling public-private collaboration in a precompetitive arena
Guillaume Paillard, Philip Cochrane, Philip S Jones, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
March 18, 2017
In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer's Disease
Laura Aitken, Gemma Baillie, Andrew Pannifer, et al.
International Journal of Molecular Sciences
|
April 13, 2024
The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds
Johan Gising, Saman Honarnejad, Maaike Bras, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 6, 2003
Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening
Stephen D Pickett, Bradley S Sherborne, Trevor Wilkinson, et al.
Bioorganic & Medicinal Chemistry
|
December 15, 2006
Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties
Ronald Palin, Anton Bom, John K Clark, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 13, 2009
Rapid access towards follow-up NOP receptor agonists using a knowledge based approach
Ronald Palin, John K Clark, Louise Evans, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 14, 2011
1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pka
Wullie Arbuckle, Mark Baugh, Simone Belshaw, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 13, 2003
Identification of a novel class of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents with protein tyrosine phosphatase inhibitory activity
Kevin R Guertin, Lina Setti, Lida Qi, et al.
ACS Chemical Biology
|
June 18, 2025
High-Throughput Screening of Potent Drug-like Molecules Targeting 17β-HSD10 for the Treatment of Alzheimer's Disease and Cancer
Laura Aitken, Gemma Baillie, Andrew Pannifer, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 25, 2005
Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists
Ronald Palin, David R Barn, John K Clark, et al.
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Showing results (11-20 of 25) with videos related to
Sort By:
Page
of 3
Drug Discovery Today
|
November 27, 2015
The ELF Honest Data Broker: informatics enabling public-private collaboration in a precompetitive arena
Guillaume Paillard, Philip Cochrane, Philip S Jones, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
March 18, 2017
In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer's Disease
Laura Aitken, Gemma Baillie, Andrew Pannifer, et al.
International Journal of Molecular Sciences
|
April 13, 2024
The Discovery of New Inhibitors of Insulin-Regulated Aminopeptidase by a High-Throughput Screening of 400,000 Drug-like Compounds
Johan Gising, Saman Honarnejad, Maaike Bras, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 6, 2003
Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening
Stephen D Pickett, Bradley S Sherborne, Trevor Wilkinson, et al.
Bioorganic & Medicinal Chemistry
|
December 15, 2006
Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties
Ronald Palin, Anton Bom, John K Clark, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 13, 2009
Rapid access towards follow-up NOP receptor agonists using a knowledge based approach
Ronald Palin, John K Clark, Louise Evans, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 14, 2011
1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pka
Wullie Arbuckle, Mark Baugh, Simone Belshaw, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 13, 2003
Identification of a novel class of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents with protein tyrosine phosphatase inhibitory activity
Kevin R Guertin, Lina Setti, Lida Qi, et al.
ACS Chemical Biology
|
June 18, 2025
High-Throughput Screening of Potent Drug-like Molecules Targeting 17β-HSD10 for the Treatment of Alzheimer's Disease and Cancer
Laura Aitken, Gemma Baillie, Andrew Pannifer, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 25, 2005
Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists
Ronald Palin, David R Barn, John K Clark, et al.
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