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The Journal of Organic Chemistry
|
August 14, 2013
A constrained tricyclic nucleic acid analogue of α-L-LNA: investigating the effects of dual conformational restriction on duplex thermal stability
Stephen Hanessian, Jernej Wagger, Bradley L Merner, et al.
Angewandte Chemie (International Ed. in English)
|
August 24, 2012
Structure-based design of a highly constrained nucleic acid analogue: improved duplex stabilization by restricting sugar pucker and torsion angle γ
Stephen Hanessian, Benjamin R Schroeder, Robert D Giacometti, et al.
Chemical Communications (Cambridge, England)
|
May 23, 2012
Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs
Pradeep S Pallan, Charles R Allerson, Andres Berdeja, et al.
Molecular Therapy. Nucleic Acids
|
June 19, 2017
Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides
Michael E Østergaard, Josh Nichols, Timothy A Dwight, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2018
Evaluation of the effect of 2'-O-methyl, fluoro hexitol, bicyclo and Morpholino nucleic acid modifications on potency of GalNAc conjugated antisense oligonucleotides in mice
Thazha P Prakash, Jinghua Yu, Garth A Kinberger, et al.
Nucleic Acid Therapeutics
|
February 10, 2018
Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver
Colton M Miller, Michael Tanowitz, Aaron J Donner, et al.
Nucleic Acid Therapeutics
|
May 25, 2022
Targeted Delivery of Antisense Oligonucleotides Through Angiotensin Type 1 Receptor
Carol Kuo, Mehran Nikan, Steve T Yeh, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
April 3, 2010
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
Ryan B Paulsen, Punit P Seth, Eric E Swayze, et al.
Journal of Medicinal Chemistry
|
December 18, 2008
Short antisense oligonucleotides with novel 2'-4' conformationaly restricted nucleoside analogues show improved potency without increased toxicity in animals
Punit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
February 7, 2017
Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology
Karen L Posey, Francoise Coustry, Alka C Veerisetty, et al.
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Search research articles
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Showing results (41-50 of 108) with videos related to
Sort By:
Page
of 11
The Journal of Organic Chemistry
|
August 14, 2013
A constrained tricyclic nucleic acid analogue of α-L-LNA: investigating the effects of dual conformational restriction on duplex thermal stability
Stephen Hanessian, Jernej Wagger, Bradley L Merner, et al.
Angewandte Chemie (International Ed. in English)
|
August 24, 2012
Structure-based design of a highly constrained nucleic acid analogue: improved duplex stabilization by restricting sugar pucker and torsion angle γ
Stephen Hanessian, Benjamin R Schroeder, Robert D Giacometti, et al.
Chemical Communications (Cambridge, England)
|
May 23, 2012
Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs
Pradeep S Pallan, Charles R Allerson, Andres Berdeja, et al.
Molecular Therapy. Nucleic Acids
|
June 19, 2017
Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides
Michael E Østergaard, Josh Nichols, Timothy A Dwight, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2018
Evaluation of the effect of 2'-O-methyl, fluoro hexitol, bicyclo and Morpholino nucleic acid modifications on potency of GalNAc conjugated antisense oligonucleotides in mice
Thazha P Prakash, Jinghua Yu, Garth A Kinberger, et al.
Nucleic Acid Therapeutics
|
February 10, 2018
Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver
Colton M Miller, Michael Tanowitz, Aaron J Donner, et al.
Nucleic Acid Therapeutics
|
May 25, 2022
Targeted Delivery of Antisense Oligonucleotides Through Angiotensin Type 1 Receptor
Carol Kuo, Mehran Nikan, Steve T Yeh, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
April 3, 2010
Inhibitor-induced structural change in the HCV IRES domain IIa RNA
Ryan B Paulsen, Punit P Seth, Eric E Swayze, et al.
Journal of Medicinal Chemistry
|
December 18, 2008
Short antisense oligonucleotides with novel 2'-4' conformationaly restricted nucleoside analogues show improved potency without increased toxicity in animals
Punit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
February 7, 2017
Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology
Karen L Posey, Francoise Coustry, Alka C Veerisetty, et al.
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of 11