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Current Organic Synthesis|January 7, 2022
A Facile Total Synthesis of Kilogram-Scale Production of SKLB1039: A Novel and Selective Hexahydroisoquinolin-Containing EZH2 InhibitorQiang Feng, Qiangsheng Zhang, Hualong He, et al.
Pharmacological Research|March 8, 2022
Focus on the classical and non-classical functions of EZH2: Guide the development of inhibitors and degradersQiangsheng Zhang, Hongling Yang, Qiang Feng, et al.
European Journal of Medicinal Chemistry|December 25, 2022
Design, synthesis and evaluation of antitumor activity of selective PRMT6 inhibitorsQiangsheng Zhang, Jiaying Cao, Yiqian Zhang, et al.
Expert Opinion on Therapeutic Patents|April 25, 2023
A patent review of EZH2 inhibitors from 2017 and beyondGuoquan Wan, Huan Feng, Chang Su, et al.
Life Sciences|March 1, 2024
Targeting type I PRMTs as promising targets for the treatment of pulmonary disorders: Asthma, COPD, lung cancer, PF, and PHShuyan Zhou, Qiangsheng Zhang, Honglin Yang, et al.
Biochemical Pharmacology|March 10, 2023
Pharmacological inhibition of EZH2 by ZLD1039 suppresses tumor growth and pulmonary metastasis in melanoma cells in vitro and in vivoYongxia Zhu, Lidan Zhang, Xuejiao Song, et al.
Molecular and Cellular Biochemistry|May 18, 2023
Pharmacological inhibition of EZH2 using a covalent inhibitor suppresses human ovarian cancer cell migration and invasionLihong Shi, Qiangsheng Zhang, Shirui Zhu, et al.
Bioorganic Chemistry|May 16, 2024
Discovery of a first-in-class degrader for the protein arginine methyltransferase 6 (PRMT6)Hongling Yang, Qiangsheng Zhang, Shuyan Zhou, et al.
Bioorganic & Medicinal Chemistry Letters|January 22, 2020
Design and synthesis of (E)-1,2-diphenylethene-based EZH2 inhibitorsHualong He, Xi Hu, Fei Teng, et al.
Bioorganic Chemistry|March 3, 2020
Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding siteXi Hu, Lu Li, Qiangsheng Zhang, et al.
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