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Biorxiv : the Preprint Server for Biology
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June 9, 2023
The p97/VCP adapter UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions
Julian R Braxton, Chad R Altobelli, Maxwell R Tucker, et al.
ACS Chemical Biology
|
November 16, 2020
Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers
Eline Sijbesma, Bente A Somsen, Galen P Miley, et al.
Journal of the American Chemical Society
|
March 17, 2023
Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERRγ Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach
Bente A Somsen, Rick J C Schellekens, Carlo J A Verhoef, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 19, 2014
A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1
T Justin Rettenmaier, Jack D Sadowsky, Nathan D Thomsen, et al.
ACS Chemical Biology
|
June 7, 2013
A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels
Sviatoslav N Bagriantsev, Kean-Hooi Ang, Alejandra Gallardo-Godoy, et al.
Journal of the American Chemical Society
|
February 2, 2019
Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers
Eline Sijbesma, Kenneth K Hallenbeck, Seppe Leysen, et al.
ACS Medicinal Chemistry Letters
|
June 17, 2021
Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers
Eline Sijbesma, Kenneth K Hallenbeck, Sebastian A Andrei, et al.
Combinatorial Chemistry & High Throughput Screening
|
March 26, 2014
UCSF Small Molecule Discovery Center: innovation, collaboration and chemical biology in the Bay Area
Michelle R Arkin, Kenny K H Ang, Steven Chen, et al.
Journal of the American Chemical Society
|
July 12, 2022
Adaptor-Specific Antibody Fragment Inhibitors for the Intracellular Modulation of p97 (VCP) Protein-Protein Interactions
Ziwen Jiang, Yu-Hsuan Kuo, Mengqi Zhong, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
September 26, 2017
A Liquid Chromatography/Mass Spectrometry Method for Screening Disulfide Tethering Fragments
Kenneth K Hallenbeck, Julia L Davies, Connie Merron, et al.
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Search research articles
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Showing results (51-60 of 128) with videos related to
Sort By:
Page
of 13
Biorxiv : the Preprint Server for Biology
|
June 9, 2023
The p97/VCP adapter UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions
Julian R Braxton, Chad R Altobelli, Maxwell R Tucker, et al.
ACS Chemical Biology
|
November 16, 2020
Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers
Eline Sijbesma, Bente A Somsen, Galen P Miley, et al.
Journal of the American Chemical Society
|
March 17, 2023
Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERRγ Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach
Bente A Somsen, Rick J C Schellekens, Carlo J A Verhoef, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 19, 2014
A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1
T Justin Rettenmaier, Jack D Sadowsky, Nathan D Thomsen, et al.
ACS Chemical Biology
|
June 7, 2013
A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels
Sviatoslav N Bagriantsev, Kean-Hooi Ang, Alejandra Gallardo-Godoy, et al.
Journal of the American Chemical Society
|
February 2, 2019
Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers
Eline Sijbesma, Kenneth K Hallenbeck, Seppe Leysen, et al.
ACS Medicinal Chemistry Letters
|
June 17, 2021
Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers
Eline Sijbesma, Kenneth K Hallenbeck, Sebastian A Andrei, et al.
Combinatorial Chemistry & High Throughput Screening
|
March 26, 2014
UCSF Small Molecule Discovery Center: innovation, collaboration and chemical biology in the Bay Area
Michelle R Arkin, Kenny K H Ang, Steven Chen, et al.
Journal of the American Chemical Society
|
July 12, 2022
Adaptor-Specific Antibody Fragment Inhibitors for the Intracellular Modulation of p97 (VCP) Protein-Protein Interactions
Ziwen Jiang, Yu-Hsuan Kuo, Mengqi Zhong, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
September 26, 2017
A Liquid Chromatography/Mass Spectrometry Method for Screening Disulfide Tethering Fragments
Kenneth K Hallenbeck, Julia L Davies, Connie Merron, et al.
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of 13