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Proceedings of the National Academy of Sciences of the United States of America
|
April 28, 2026
Restoring the 14-3-3/CRAF regulatory interaction in Noonan syndrome using molecular glues
Johanna M Virta, Holly R Vickery, Markella Konstantinidou, et al.
Nature Reviews. Drug Discovery
|
September 22, 2015
Tackling reproducibility in academic preclinical drug discovery
Stephen V Frye, Michelle R Arkin, Cheryl H Arrowsmith, et al.
Journal of the American Chemical Society
|
March 27, 2003
Discovery of a potent small molecule IL-2 inhibitor through fragment assembly
Andrew C Braisted, Johan D Oslob, Warren L Delano, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 3, 2005
Identification of nonpeptidic small-molecule inhibitors of interleukin-2
Nathan D Waal, Wenjin Yang, Johan D Oslob, et al.
Journal of Biomolecular Screening
|
February 19, 2015
A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP
Michael S Chimenti, Stacie L Bulfer, R Jeffrey Neitz, et al.
ACS Chemical Neuroscience
|
May 6, 2022
Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model
Marcus Y Chin, Kean-Hooi Ang, Julia Davies, et al.
Mbio
|
November 1, 2018
Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen <i>Balamuthia mandrillaris</i>
Matthew T Laurie, Corin V White, Hanna Retallack, et al.
Plos One
|
December 19, 2019
Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening
Mateo I Sanchez, Laura E de Vries, Christine Lehmann, et al.
Plos One
|
April 27, 2010
Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II
Rachael E Hawtin, David E Stockett, Jo Ann W Byl, et al.
RSC Chemical Biology
|
March 8, 2024
Identifying ligands for the PHD1 finger of KDM5A through high-throughput screening
Gloria Ortiz, James E Longbotham, Sophia L Qin, et al.
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Search research articles
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Showing results (61-70 of 128) with videos related to
Sort By:
Page
of 13
Proceedings of the National Academy of Sciences of the United States of America
|
April 28, 2026
Restoring the 14-3-3/CRAF regulatory interaction in Noonan syndrome using molecular glues
Johanna M Virta, Holly R Vickery, Markella Konstantinidou, et al.
Nature Reviews. Drug Discovery
|
September 22, 2015
Tackling reproducibility in academic preclinical drug discovery
Stephen V Frye, Michelle R Arkin, Cheryl H Arrowsmith, et al.
Journal of the American Chemical Society
|
March 27, 2003
Discovery of a potent small molecule IL-2 inhibitor through fragment assembly
Andrew C Braisted, Johan D Oslob, Warren L Delano, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 3, 2005
Identification of nonpeptidic small-molecule inhibitors of interleukin-2
Nathan D Waal, Wenjin Yang, Johan D Oslob, et al.
Journal of Biomolecular Screening
|
February 19, 2015
A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP
Michael S Chimenti, Stacie L Bulfer, R Jeffrey Neitz, et al.
ACS Chemical Neuroscience
|
May 6, 2022
Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model
Marcus Y Chin, Kean-Hooi Ang, Julia Davies, et al.
Mbio
|
November 1, 2018
Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen <i>Balamuthia mandrillaris</i>
Matthew T Laurie, Corin V White, Hanna Retallack, et al.
Plos One
|
December 19, 2019
Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening
Mateo I Sanchez, Laura E de Vries, Christine Lehmann, et al.
Plos One
|
April 27, 2010
Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II
Rachael E Hawtin, David E Stockett, Jo Ann W Byl, et al.
RSC Chemical Biology
|
March 8, 2024
Identifying ligands for the PHD1 finger of KDM5A through high-throughput screening
Gloria Ortiz, James E Longbotham, Sophia L Qin, et al.
Page
of 13