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Journal of Medicinal Chemistry|October 7, 2025
Optimization of 2,8-Diaryl-1,5-naphthyridines as Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo EfficacyGodwin A Dziwornu, Donald Seanego, Stephen Fienberg, et al.
ACS Infectious Diseases|November 3, 2022
1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosisVinayak Singh, Anna E Grzegorzewicz, Stephen Fienberg, et al.
Journal of Medicinal Chemistry|August 14, 2025
Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection ModelGodwin A Dziwornu, Mmakwena M Mmonwa, Dina Coertzen, et al.
Bioorganic & Medicinal Chemistry Letters|June 20, 2015
Whole cell screen based identification of spiropiperidines with potent antitubercular propertiesSubramanyam J Tantry, Giulia Degiacomi, Sreevalli Sharma, et al.
Journal of Medicinal Chemistry|August 20, 2021
1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosisLutete Peguy Khonde, Rudolf Müller, Grant A Boyle, et al.
Journal of Medicinal Chemistry|January 4, 2021
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action StudiesCandice Soares de Melo, Vinayak Singh, Alissa Myrick, et al.
Bioorganic & Medicinal Chemistry Letters|January 11, 2014
Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacyRamesh R Kale, Manoj G Kale, David Waterson, et al.
Journal of Medicinal Chemistry|October 4, 2013
Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase BManoj G Kale, Anandkumar Raichurkar, Shahul Hameed P, et al.
Journal of Medicinal Chemistry|November 18, 2017
Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification StudiesColin R Wilson, Richard K Gessner, Atica Moosa, et al.
Journal of Medicinal Chemistry|June 25, 2024
2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo EfficacyGodwin Akpeko Dziwornu, Donald Seanego, Stephen Fienberg, et al.
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