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Journal of Pharmacokinetics and Pharmacodynamics|May 31, 2001
In vivo cerebral pharmacokinetics and pharmacodynamics of diazepam and midazolam after short intravenous infusion administration in sheepR N Upton, G L Ludbrook, C Grant, et al.
Intensive Care Medicine|March 31, 2001
Epinephrine, norepinephrine and dopamine infusions decrease propofol concentrations during continuous propofol infusion in an ovine modelJ A Myburgh, R N Upton, C Grant, et al.
Anaesthesia and Intensive Care|December 26, 2002
The cerebrovascular effects of adrenaline, noradrenaline and dopamine infusions under propofol and isoflurane anaesthesia in sheepJ A Myburgh, R N Upton, C Grant, et al.
Anesthesia and Analgesia|September 4, 1999
Cardiac output is a determinant of the initial concentrations of propofol after short-infusion administrationR N Upton, G L Ludbrook, C Grant, et al.
Anaesthesia and Intensive Care|February 1, 1996
Cerebral effects of propofol following bolus administration in sheepG L Ludbrook, R N Upton, C Grant, et al.
Anesthesiology|October 6, 2000
The effect of altered cerebral blood flow on the cerebral kinetics of thiopental and propofol in sheepR N Upton, G L Ludbrook, C Grant, et al.
Anaesthesia and Intensive Care|August 1, 1996
Brain and blood concentrations of propofol after rapid intravenous injection in sheep, and their relationships to cerebral effectsG L Ludbrook, R N Upton, C Grant, et al.
The Journal of Pharmacy and Pharmacology|March 14, 2000
Development and validation of a recirculatory physiological model of the myocardial concentrations of lignocaine after intravenous administration in sheepR N Upton, D A Zheng, C Grant, et al.
British Journal of Anaesthesia|September 21, 2004
Recirculatory model of fentanyl disposition with the brain as the target organR N Upton, C Grant, A M Martinez, et al.
Journal of Pharmacokinetics and Biopharmaceutics|February 1, 1996
In vivo relationships between the cerebral pharmacokinetics and pharmacodynamics of thiopentone in sheep after short-term administrationR N Upton, G L Ludbrook, C Grant, et al.
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