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R Scott Obach

Showing results (91-100 of 193) with videos related to

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Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 31, 2009
Cross-species comparison of the metabolism and excretion of zoniporide: contribution of aldehyde oxidase to interspecies differencesDeepak Dalvie, Chenghong Zhang, Weichao Chen, et al.
Journal of Pharmaceutical Sciences|April 17, 2017
Prediction of Losartan-Active Carboxylic Acid Metabolite Exposure Following Losartan Administration Using Static and Physiologically Based Pharmacokinetic ModelsHoa Q Nguyen, Jian Lin, Emi Kimoto, et al.
Bioorganic & Medicinal Chemistry Letters|May 3, 2018
Harnessing biosynthesis and quantitative NMR for late stage functionalization of lead molecules: Application to the M1 positive allosteric modulator (PAM) programMichael A Brodney, Raman Sharma, John T Lazzaro, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 12, 2019
Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench ApproachSravani Adusumalli, Rohitash Jamwal, R Scott Obach, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|March 31, 2011
From definition to implementation: a cross-industry perspective of past, current and future MIST strategiesAngus N R Nedderman, Gordon J Dear, Stephanie North, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 3, 2010
Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolitesWendy WeiWei Wang, Salman R Khetani, Stacy Krzyzewski, et al.
Drug Metabolism and Pharmacokinetics|March 9, 2011
Metabolism of a dopamine receptor partial agonist in rats, including an unusual N-dearylation reactionSabrina X Zhao, Wendy Weiwei Wang, Gregory S Walker, et al.
Clinical Pharmacology and Therapeutics|December 13, 2005
In vitro cytochrome P450 inhibition data and the prediction of drug-drug interactions: qualitative relationships, quantitative predictions, and the rank-order approachR Scott Obach, Robert L Walsky, Karthik Venkatakrishnan, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|September 7, 2016
An exposure-response analysis based on rifampin suggests CYP3A4 induction is driven by AUC: an in vitro investigationCheng Chang, Xin Yang, Odette A Fahmi, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 14, 2003
Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: comparison with fluoxetine and quinidineKirk M Bertelsen, Karthik Venkatakrishnan, Lisa L Von Moltke, et al.
Pageof 20

Showing results (91-100 of 193) with videos related to

Sort By:
Pageof 20
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 31, 2009
Cross-species comparison of the metabolism and excretion of zoniporide: contribution of aldehyde oxidase to interspecies differencesDeepak Dalvie, Chenghong Zhang, Weichao Chen, et al.
Journal of Pharmaceutical Sciences|April 17, 2017
Prediction of Losartan-Active Carboxylic Acid Metabolite Exposure Following Losartan Administration Using Static and Physiologically Based Pharmacokinetic ModelsHoa Q Nguyen, Jian Lin, Emi Kimoto, et al.
Bioorganic & Medicinal Chemistry Letters|May 3, 2018
Harnessing biosynthesis and quantitative NMR for late stage functionalization of lead molecules: Application to the M1 positive allosteric modulator (PAM) programMichael A Brodney, Raman Sharma, John T Lazzaro, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 12, 2019
Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench ApproachSravani Adusumalli, Rohitash Jamwal, R Scott Obach, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|March 31, 2011
From definition to implementation: a cross-industry perspective of past, current and future MIST strategiesAngus N R Nedderman, Gordon J Dear, Stephanie North, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 3, 2010
Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolitesWendy WeiWei Wang, Salman R Khetani, Stacy Krzyzewski, et al.
Drug Metabolism and Pharmacokinetics|March 9, 2011
Metabolism of a dopamine receptor partial agonist in rats, including an unusual N-dearylation reactionSabrina X Zhao, Wendy Weiwei Wang, Gregory S Walker, et al.
Clinical Pharmacology and Therapeutics|December 13, 2005
In vitro cytochrome P450 inhibition data and the prediction of drug-drug interactions: qualitative relationships, quantitative predictions, and the rank-order approachR Scott Obach, Robert L Walsky, Karthik Venkatakrishnan, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|September 7, 2016
An exposure-response analysis based on rifampin suggests CYP3A4 induction is driven by AUC: an in vitro investigationCheng Chang, Xin Yang, Odette A Fahmi, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 14, 2003
Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: comparison with fluoxetine and quinidineKirk M Bertelsen, Karthik Venkatakrishnan, Lisa L Von Moltke, et al.
Pageof 20