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Xenobiotica; the Fate of Foreign Compounds in Biological Systems|May 20, 2025
Meeting report: DMDG peptide and oligonucleotide ADME workshop 2024Inga Bjørnsdottir, Ralf Lotz, Bo Lindmark, et al.
Pharmaceutics|November 14, 2019
Muscle to Brain Partitioning as Measure of Transporter-Mediated Efflux at the Rat Blood-Brain Barrier and Its Implementation into Compound Optimization in Drug DiscoveryYunhai Cui, Ralf Lotz, Hermann Rapp, et al.
Clinical Pharmacokinetics|April 25, 2019
Clinical Pharmacokinetics and Pharmacodynamics of NintedanibSven Wind, Ulrike Schmid, Matthias Freiwald, et al.
Drug Discovery Today|November 9, 2024
Beyond CL and VSS: A comprehensive approach to human pharmacokinetic predictionsAnneke Himstedt, Hermann Rapp, Peter Stopfer, et al.
European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V|February 1, 2019
Characterization of the GI transit conditions in Beagle dogs with a telemetric motility capsuleMirko Koziolek, Michael Grimm, Tabea Bollmann, et al.
Bioorganic & Medicinal Chemistry Letters|May 20, 2008
3,5-Dihydro-imidazo[4,5-d]pyridazin-4-ones: a class of potent DPP-4 inhibitorsMatthias Eckhardt, Norbert Hauel, Frank Himmelsbach, et al.
Journal of Medicinal Chemistry|June 16, 2009
Design, synthesis, and evaluation of indolinones as triple angiokinase inhibitors and the discovery of a highly specific 6-methoxycarbonyl-substituted indolinone (BIBF 1120)Gerald J Roth, Armin Heckel, Florian Colbatzky, et al.
Bioorganic & Medicinal Chemistry Letters|January 26, 2010
Discovery of olodaterol, a novel inhaled beta2-adrenoceptor agonist with a 24 h bronchodilatory efficacyThierry Bouyssou, Christoph Hoenke, Klaus Rudolf, et al.
Journal of Medicinal Chemistry|December 7, 2007
8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetesMatthias Eckhardt, Elke Langkopf, Michael Mark, et al.
The AAPS Journal|October 16, 2020
Cell-to-Medium Concentration Ratio Overshoot in the Uptake of Statins by Human Hepatocytes in Suspension, but Not in Monolayer: Kinetic Analysis Suggesting a Partial Loss of Functional OATP1BsWooin Lee, Satoshi Koyama, Kiyoe Morita, et al.
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