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Combinatorial Chemistry & High Throughput Screening|September 24, 2005
HTS quality control and data analysis: a process to maximize information from a high-throughput screenRamesh Padmanabha, Lynda Cook, James GillAnalytical Biochemistry|March 26, 2003
Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic interventionLaura E Zawadzke, Ping Wu, Lynda Cook, et al.Journal of Biomolecular Screening|February 3, 2007
A simple strategy for mitigating the effect of data variability on the identification of active chemotypes from high-throughput screening dataStephen R Johnson, Ramesh Padmanabha, Wayne Vaccaro, et al.Bioorganic & Medicinal Chemistry Letters|July 12, 2005
Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycinShuhao Shi, Shirong Zhu, Samuel W Gerritz, et al.ACS Medicinal Chemistry Letters|March 19, 2020
Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit TriageAmy C Hart, Lynn Abell, Junqing Guo, et al.Bioorganic & Medicinal Chemistry Letters|March 27, 2007
2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitorsJames J Li, Haixia Wang, Joseph A Tino, et al.Bioorganic & Medicinal Chemistry Letters|September 18, 2007
Amino-caprolactam derivatives as gamma-secretase inhibitorsMichael F Parker, Joanne J Bronson, Donna M Barten, et al.Journal of Medicinal Chemistry|December 13, 2006
2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitorJagabandhu Das, Ping Chen, Derek Norris, et al.Journal of Medicinal Chemistry|October 4, 2012
Acyl guanidine inhibitors of β-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesisSamuel W Gerritz, Weixu Zhai, Shuhao Shi, et al.Medicinal Chemistry Research : an International Journal for Rapid Communications on Design and Mechanisms of Action of Biologically Active Agents|June 26, 2023
Discovery of pyrrolo[2,1-<i>f</i>][1,2,4]triazine-based inhibitors of adaptor protein 2-associated kinase 1 for the treatment of painCarolyn D Dzierba, Bireshwar Dasgupta, George Karageorge, et al.Pageof 2