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Journal of Molecular Biology|June 20, 2017
Structure and Function of Viral Deubiquitinating EnzymesBen A Bailey-Elkin, Robert C M Knaap, Marjolein Kikkert, et al.
Methods in Enzymology|March 10, 2019
Profiling DUBs and Ubl-specific proteases with activity-based probesPaul P Geurink, Gerbrand J van der Heden van Noort, Monique P C Mulder, et al.
Veterinary Microbiology|May 16, 2015
In vivo assessment of equine arteritis virus vaccine improvement by disabling the deubiquitinase activity of papain-like protease 2Puck B van Kasteren, Robert C M Knaap, Paul van den Elzen, et al.
Plos Pathogens|December 14, 2023
Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesisBen A Bailey-Elkin, Robert C M Knaap, Anuradha De Silva, et al.
The Journal of Biological Chemistry|October 17, 2014
Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppressionBen A Bailey-Elkin, Robert C M Knaap, Garrett G Johnson, et al.
Plos Pathogens|October 27, 2016
Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress ResponsesHuib H Rabouw, Martijn A Langereis, Robert C M Knaap, et al.
Plos Pathogens|May 26, 2017
Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variantsWei Zhang, Ben A Bailey-Elkin, Robert C M Knaap, et al.
Nature Communications|February 28, 2023
Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinaseSebenzile K Myeni, Peter J Bredenbeek, Robert C M Knaap, et al.
Plos Pathogens|March 25, 2024
Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivoMariska van Huizen, Jonna R Bloeme-Ter Horst, Heidi L M de Gruyter, et al.
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