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Robert J Riley

Showing results (31-40 of 42) with videos related to

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Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 16, 2002
The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical propertiesRupert P Austin, Patrick Barton, Scott L Cockroft, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 23, 2008
Prediction of the pharmacokinetics of atorvastatin, cerivastatin, and indomethacin using kinetic models applied to isolated rat hepatocytesStuart W Paine, Alison J Parker, Philip Gardiner, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 9, 2007
Use of hepatocytes to assess the contribution of hepatic uptake to clearance in vivoMatthew G Soars, Ken Grime, Joanne L Sproston, et al.
Biochemical Pharmacology|April 16, 2003
Cloning and characterisation of the first drug-metabolising canine UDP-glucuronosyltransferase of the 2B subfamilyMatthew G Soars, Michelle Fettes, Audrey C O'Sullivan, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|January 15, 2014
Application of an in vitro OAT assay in drug design and optimization of renal clearanceMatthew G Soars, Patrick Barton, Lisa L Elkin, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 10, 2006
Which hydroxy? Evidence for species differences in the regioselectivity of glucuronidation in rat, dog, and human in vitro systems and dog in vivoIain J Martin, Richard J Lewis, Michael A Bernstein, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 24, 2018
Mechanistic In Vitro Studies Indicate that the Clinical Drug-Drug Interaction between Telithromycin and Simvastatin Acid Is Driven by Time-Dependent Inhibition of CYP3A4 with Minimal Effect on OATP1B1Robert Elsby, Victoria Hare, Hannah Neal, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 25, 2009
Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG cellsDermot F McGinnity, George Zhang, Jane R Kenny, et al.
Bioorganic & Medicinal Chemistry Letters|October 4, 2012
The discovery of CCR3/H1 dual antagonists with reduced hERG riskAsh Bahl, Patrick Barton, Keith Bowers, et al.
Bioorganic & Medicinal Chemistry Letters|October 2, 2012
Scaffold-hopping with zwitterionic CCR3 antagonists: identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092Ash Bahl, Patrick Barton, Keith Bowers, et al.
Pageof 5

Showing results (31-40 of 42) with videos related to

Sort By:
Pageof 5
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 16, 2002
The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical propertiesRupert P Austin, Patrick Barton, Scott L Cockroft, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 23, 2008
Prediction of the pharmacokinetics of atorvastatin, cerivastatin, and indomethacin using kinetic models applied to isolated rat hepatocytesStuart W Paine, Alison J Parker, Philip Gardiner, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 9, 2007
Use of hepatocytes to assess the contribution of hepatic uptake to clearance in vivoMatthew G Soars, Ken Grime, Joanne L Sproston, et al.
Biochemical Pharmacology|April 16, 2003
Cloning and characterisation of the first drug-metabolising canine UDP-glucuronosyltransferase of the 2B subfamilyMatthew G Soars, Michelle Fettes, Audrey C O'Sullivan, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|January 15, 2014
Application of an in vitro OAT assay in drug design and optimization of renal clearanceMatthew G Soars, Patrick Barton, Lisa L Elkin, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 10, 2006
Which hydroxy? Evidence for species differences in the regioselectivity of glucuronidation in rat, dog, and human in vitro systems and dog in vivoIain J Martin, Richard J Lewis, Michael A Bernstein, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 24, 2018
Mechanistic In Vitro Studies Indicate that the Clinical Drug-Drug Interaction between Telithromycin and Simvastatin Acid Is Driven by Time-Dependent Inhibition of CYP3A4 with Minimal Effect on OATP1B1Robert Elsby, Victoria Hare, Hannah Neal, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 25, 2009
Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG cellsDermot F McGinnity, George Zhang, Jane R Kenny, et al.
Bioorganic & Medicinal Chemistry Letters|October 4, 2012
The discovery of CCR3/H1 dual antagonists with reduced hERG riskAsh Bahl, Patrick Barton, Keith Bowers, et al.
Bioorganic & Medicinal Chemistry Letters|October 2, 2012
Scaffold-hopping with zwitterionic CCR3 antagonists: identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092Ash Bahl, Patrick Barton, Keith Bowers, et al.
Pageof 5