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Journal of Medicinal Chemistry
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June 18, 2021
Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B
David Lee Walmsley, James B Murray, Pawel Dokurno, et al.
Journal of Medicinal Chemistry
|
May 12, 2021
Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors
Csaba Weber, Melinda Sipos, Attila Paczal, et al.
ACS Omega
|
September 9, 2021
The Effect of Core Replacement on S64315, a Selective MCL-1 Inhibitor, and Its Analogues
Szabolcs Sipos, Balázs Bálint, Zoltán B Szabó, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
September 15, 2023
Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors
Edward A FitzGerald, Darius Vagrys, Giulia Opassi, et al.
ACS Chemical Neuroscience
|
January 18, 2024
Identification of a Novel Subtype-Selective α<sub>1B</sub>-Adrenoceptor Antagonist
Alaa Abdul-Ridha, Lazarus A de Zhang, Ashenafi Haileyesus Betrie, et al.
RSC Medicinal Chemistry
|
December 22, 2022
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates
S Paul Jones, James D Firth, Mary C Wheldon, et al.
Journal of Medicinal Chemistry
|
October 23, 2024
Structure-Guided Discovery of Selective USP7 Inhibitors with In Vivo Activity
Attila Vasas, Lisa Ivanschitz, Balázs Molnár, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 16, 2007
Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping
Christine M Richardson, Claire L Nunns, Douglas S Williamson, et al.
ACS Omega
|
January 26, 2026
Targeting PTPN22 at Nonorthosteric Binding SitesA Fragment Approach
Paola Di Lello, Marta M Wells, Ben Davis, et al.
RSC Medicinal Chemistry
|
November 25, 2022
PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery
Huiyong Ma, James B Murray, Huadong Luo, et al.
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of 8
Search research articles
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Showing results (51-60 of 74) with videos related to
Sort By:
Page
of 8
Journal of Medicinal Chemistry
|
June 18, 2021
Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B
David Lee Walmsley, James B Murray, Pawel Dokurno, et al.
Journal of Medicinal Chemistry
|
May 12, 2021
Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors
Csaba Weber, Melinda Sipos, Attila Paczal, et al.
ACS Omega
|
September 9, 2021
The Effect of Core Replacement on S64315, a Selective MCL-1 Inhibitor, and Its Analogues
Szabolcs Sipos, Balázs Bálint, Zoltán B Szabó, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
September 15, 2023
Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors
Edward A FitzGerald, Darius Vagrys, Giulia Opassi, et al.
ACS Chemical Neuroscience
|
January 18, 2024
Identification of a Novel Subtype-Selective α<sub>1B</sub>-Adrenoceptor Antagonist
Alaa Abdul-Ridha, Lazarus A de Zhang, Ashenafi Haileyesus Betrie, et al.
RSC Medicinal Chemistry
|
December 22, 2022
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates
S Paul Jones, James D Firth, Mary C Wheldon, et al.
Journal of Medicinal Chemistry
|
October 23, 2024
Structure-Guided Discovery of Selective USP7 Inhibitors with In Vivo Activity
Attila Vasas, Lisa Ivanschitz, Balázs Molnár, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 16, 2007
Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping
Christine M Richardson, Claire L Nunns, Douglas S Williamson, et al.
ACS Omega
|
January 26, 2026
Targeting PTPN22 at Nonorthosteric Binding SitesA Fragment Approach
Paola Di Lello, Marta M Wells, Ben Davis, et al.
RSC Medicinal Chemistry
|
November 25, 2022
PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery
Huiyong Ma, James B Murray, Huadong Luo, et al.
Page
of 8