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Roxanne K Kunz

Showing results (1-10 of 14) with videos related to

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Journal of the American Chemical Society|March 10, 2005
Enantioselective organocatalytic cyclopropanations. The identification of a new class of iminium catalyst based upon directed electrostatic activationRoxanne K Kunz, David W C MacMillan
Organic Letters|April 27, 2002
Diastereoselective synthesis of the endo- and exo-spirotetronate subunits of the quartromicins. The first enantioselective Diels-Alder reaction of an acyclic (Z)-1,3-dieneWilliam R Roush, Chris Limberakis, Roxanne K Kunz, et al.
Bioorganic & Medicinal Chemistry Letters|October 10, 2012
Use of structure based design to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A (PDE10A) inhibitors against phosphodiesterase 3 (PDE3)Essa Hu, Roxanne K Kunz, Shannon Rumfelt, et al.
Bioorganic & Medicinal Chemistry Letters|February 28, 2012
Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitorsEssa Hu, Roxanne K Kunz, Shannon Rumfelt, et al.
ACS Medicinal Chemistry Letters|July 21, 2016
Discovery of Phosphodiesterase 10A (PDE10A) PET Tracer AMG 580 to Support Clinical StudiesEssa Hu, Ning Chen, Roxanne K Kunz, et al.
Journal of Medicinal Chemistry|October 10, 2013
Design, optimization, and biological evaluation of novel keto-benzimidazoles as potent and selective inhibitors of phosphodiesterase 10A (PDE10A)Essa Hu, Roxanne K Kunz, Ning Chen, et al.
Bioorganic & Medicinal Chemistry Letters|August 30, 2008
Discovery of amido-benzisoxazoles as potent c-Kit inhibitorsRoxanne K Kunz, Shannon Rumfelt, Ning Chen, et al.
Journal of Medicinal Chemistry|May 2, 2008
Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-KitEssa Hu, Andrew Tasker, Ryan D White, et al.
Journal of Medicinal Chemistry|May 3, 2012
Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracerEssa Hu, Ji Ma, Christopher Biorn, et al.
Journal of Medicinal Chemistry|March 12, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine seriesNobuko Nishimura, Mark H Norman, Longbin Liu, et al.
Pageof 2

Showing results (1-10 of 14) with videos related to

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Pageof 2
Journal of the American Chemical Society|March 10, 2005
Enantioselective organocatalytic cyclopropanations. The identification of a new class of iminium catalyst based upon directed electrostatic activationRoxanne K Kunz, David W C MacMillan
Organic Letters|April 27, 2002
Diastereoselective synthesis of the endo- and exo-spirotetronate subunits of the quartromicins. The first enantioselective Diels-Alder reaction of an acyclic (Z)-1,3-dieneWilliam R Roush, Chris Limberakis, Roxanne K Kunz, et al.
Bioorganic & Medicinal Chemistry Letters|October 10, 2012
Use of structure based design to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A (PDE10A) inhibitors against phosphodiesterase 3 (PDE3)Essa Hu, Roxanne K Kunz, Shannon Rumfelt, et al.
Bioorganic & Medicinal Chemistry Letters|February 28, 2012
Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitorsEssa Hu, Roxanne K Kunz, Shannon Rumfelt, et al.
ACS Medicinal Chemistry Letters|July 21, 2016
Discovery of Phosphodiesterase 10A (PDE10A) PET Tracer AMG 580 to Support Clinical StudiesEssa Hu, Ning Chen, Roxanne K Kunz, et al.
Journal of Medicinal Chemistry|October 10, 2013
Design, optimization, and biological evaluation of novel keto-benzimidazoles as potent and selective inhibitors of phosphodiesterase 10A (PDE10A)Essa Hu, Roxanne K Kunz, Ning Chen, et al.
Bioorganic & Medicinal Chemistry Letters|August 30, 2008
Discovery of amido-benzisoxazoles as potent c-Kit inhibitorsRoxanne K Kunz, Shannon Rumfelt, Ning Chen, et al.
Journal of Medicinal Chemistry|May 2, 2008
Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-KitEssa Hu, Andrew Tasker, Ryan D White, et al.
Journal of Medicinal Chemistry|May 3, 2012
Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracerEssa Hu, Ji Ma, Christopher Biorn, et al.
Journal of Medicinal Chemistry|March 12, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine seriesNobuko Nishimura, Mark H Norman, Longbin Liu, et al.
Pageof 2