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Medrxiv : the Preprint Server for Health Sciences|February 12, 2026
Primary Amoebic Meningoencephalitis caused by Complement C2 DeficiencyJian Cui, Colleen M Roark, Nerea Domínguez-Pinilla, et al.Cell Reports|February 22, 2023
Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cellsJustin Jacobse, Rachel E Brown, Jing Li, et al.Bioorganic & Medicinal Chemistry|January 5, 2019
Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitorDavid Sperandio, Vangelis Aktoudianakis, Kerim Babaoglu, et al.Journal of Medicinal Chemistry|October 4, 2016
Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late INai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic PropertiesJeff A Zablocki, Elfatih Elzein, Xiaofen Li, et al.Nature Immunology|August 22, 2018
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiencyXiao-Fei Kong, Ruben Martinez-Barricarte, James Kennedy, et al.The Journal of Experimental Medicine|July 13, 2016
Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsetsCindy S Ma, Natalie Wong, Geetha Rao, et al.The Journal of Clinical Investigation|October 8, 2021
Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agentsRomain Lévy, David Langlais, Vivien Béziat, et al.The Journal of Experimental Medicine|August 26, 2015
Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndromeAlexandra Y Kreins, Michael J Ciancanelli, Satoshi Okada, et al.Science Immunology|December 23, 2018
Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variantStéphanie Boisson-Dupuis, Noe Ramirez-Alejo, Zhi Li, et al.Science Immunology|January 20, 2023
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency, Oriol Fornes, Alicia Jia, et al.Pageof 6