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Bioorganic & Medicinal Chemistry Letters
|
December 17, 2013
Modulating the interaction between CDK2 and cyclin A with a quinoline-based inhibitor
Yongqi Deng, Gerald W Shipps, Lianyun Zhao, et al.
Nature Communications
|
January 2, 2025
Targeting chromosomally unstable tumors with a selective KIF18A inhibitor
Aaron F Phillips, Rumin Zhang, Mia Jaffe, et al.
Therapeutics and Clinical Risk Management
|
January 14, 2021
Clinical Features for Severely and Critically Ill Patients with COVID-19 in Shandong: A Retrospective Cohort Study
Shengyu Zhou, Jiawei Xu, Wenqing Sun, et al.
Journal of Medicinal Chemistry
|
March 29, 2022
Lead Optimization to Advance Protease-Activated Receptor-1 Antagonists in Early Discovery
Mihirbaran Mandal, Maria Madeira, Rupesh P Amin, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 13, 2024
Discovery of sulfone containing metallo-β-lactamase inhibitors with reduced bacterial cell efflux and histamine release issues
Frank Bennett, Yuhua Huang, Shuzhi Dong, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 3, 2015
Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors
Brian A McKittrick, John P Caldwell, Thomas Bara, et al.
Journal of Medicinal Chemistry
|
April 21, 2007
Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization
Andrew J Prongay, Zhuyan Guo, Nanhua Yao, et al.
Journal of Synchrotron Radiation
|
April 19, 2008
Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034
Vincent Madison, Andrew J Prongay, Zhuyan Guo, et al.
Nature
|
September 30, 2015
Selective small-molecule inhibition of an RNA structural element
John A Howe, Hao Wang, Thierry O Fischmann, et al.
Cancer Discovery
|
April 26, 2013
Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors
Erick J Morris, Sharda Jha, Clifford R Restaino, et al.
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Search research articles
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Showing results (61-70 of 77) with videos related to
Sort By:
Page
of 8
Bioorganic & Medicinal Chemistry Letters
|
December 17, 2013
Modulating the interaction between CDK2 and cyclin A with a quinoline-based inhibitor
Yongqi Deng, Gerald W Shipps, Lianyun Zhao, et al.
Nature Communications
|
January 2, 2025
Targeting chromosomally unstable tumors with a selective KIF18A inhibitor
Aaron F Phillips, Rumin Zhang, Mia Jaffe, et al.
Therapeutics and Clinical Risk Management
|
January 14, 2021
Clinical Features for Severely and Critically Ill Patients with COVID-19 in Shandong: A Retrospective Cohort Study
Shengyu Zhou, Jiawei Xu, Wenqing Sun, et al.
Journal of Medicinal Chemistry
|
March 29, 2022
Lead Optimization to Advance Protease-Activated Receptor-1 Antagonists in Early Discovery
Mihirbaran Mandal, Maria Madeira, Rupesh P Amin, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 13, 2024
Discovery of sulfone containing metallo-β-lactamase inhibitors with reduced bacterial cell efflux and histamine release issues
Frank Bennett, Yuhua Huang, Shuzhi Dong, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 3, 2015
Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors
Brian A McKittrick, John P Caldwell, Thomas Bara, et al.
Journal of Medicinal Chemistry
|
April 21, 2007
Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization
Andrew J Prongay, Zhuyan Guo, Nanhua Yao, et al.
Journal of Synchrotron Radiation
|
April 19, 2008
Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034
Vincent Madison, Andrew J Prongay, Zhuyan Guo, et al.
Nature
|
September 30, 2015
Selective small-molecule inhibition of an RNA structural element
John A Howe, Hao Wang, Thierry O Fischmann, et al.
Cancer Discovery
|
April 26, 2013
Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors
Erick J Morris, Sharda Jha, Clifford R Restaino, et al.
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of 8