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Biorxiv : the Preprint Server for Biology|July 28, 2023
Non-coding sequence variation reveals fragility within interleukin 2 feedback circuitry and shapes autoimmune disease riskDimitre R Simeonov, Kyemyung Park, Jessica T Cortez, et al.Journal of Immunology (Baltimore, Md. : 1950)|March 12, 2025
Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetesLauren E Higdon, Laura A Cooney, Elisavet Serti, et al.Science Immunology|October 27, 2023
Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central toleranceJun Hyung Sin, Juliana Sucharov, Sujit Kashyap, et al.The Journal of Clinical Investigation|April 17, 2008
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in AireMaureen A Su, Karen Giang, Kristina Zumer, et al.Immunity|September 3, 2013
Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cellsJames M Gardner, Todd C Metzger, Eileen J McMahon, et al.Nature Communications|February 18, 2021
Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medullaJhoanne L Bautista, Nathan T Cramer, Corey N Miller, et al.Nature Methods|April 24, 2024
De novo identification of CD4+ T cell epitopesPaul M Zdinak, Nishtha Trivedi, Stephanie Grebinoski, et al.Science Immunology|November 12, 2021
Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epitheliumJiaxi Wang, Caleb A Lareau, Jhoanne L Bautista, et al.JCI Insight|September 22, 2017
Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunityPearl Bakhru, Meng-Lei Zhu, Hsing-Hui Wang, et al.Immunity|February 3, 2019
A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T CellsFrédéric Van Gool, Michelle L T Nguyen, Maxwell R Mumbach, et al.Pageof 19