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Brain Communications|February 9, 2023
Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approachesEdward J Smith, Kirupa Sathasivam, Christian Landles, et al.Plos Currents|February 22, 2014
The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's DiseaseVahri Beaumont, Larry Park, Arash Rassoulpour, et al.Cell Reports|September 1, 2021
FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's diseaseRobert Goold, Joseph Hamilton, Thomas Menneteau, et al.Proceedings of the National Academy of Sciences of the United States of America|January 24, 2013
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington diseaseKirupa Sathasivam, Andreas Neueder, Theresa A Gipson, et al.Journal of Neuroscience Research|July 9, 2019
Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin geneNicholas R Franich, Miriam A Hickey, Chunni Zhu, et al.The European Journal of Neuroscience|November 22, 2012
Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse modelsEric A Horne, Jonathan Coy, Katie Swinney, et al.Cell|August 2, 2016
UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the ProteasomeRoland Hjerpe, John S Bett, Matthew J Keuss, et al.Diabetes|November 6, 2008
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's diseaseBronwen Martin, Erin Golden, Olga D Carlson, et al.Brain : a Journal of Neurology|July 6, 2022
Alternative processing of human HTT mRNA with implications for Huntington's disease therapeuticsSandra Fienko, Christian Landles, Kirupa Sathasivam, et al.The EMBO Journal|August 7, 2020
TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease modelsRamanath Narayana Hegde, Anass Chiki, Lara Petricca, et al.Pageof 38