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Acta Crystallographica. Section E, Structure Reports Online|May 19, 2011
5-Bromo-1H-thieno[2,3-d]imidazoleFen Wang, Sacha Ninkovic, Michael Collins, et al.Bioorganic & Medicinal Chemistry|May 13, 2015
Effect of water solvation on the lipophilicity of isomeric pyrimidine-carboxamidesMaria Angelica Linton, Benjamin J Burke, Ted W Johnson, et al.Molecular Cancer Therapeutics|August 30, 2008
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1Alessandra Blasina, Jill Hallin, Enhong Chen, et al.Bioorganic & Medicinal Chemistry Letters|July 4, 2012
Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTORPhuong T Le, Hengmiao Cheng, Sacha Ninkovic, et al.Journal of Medicinal Chemistry|September 25, 2007
Structure-based design and synthesis of (5-arylamino-2H-pyrazol-3-yl)-biphenyl-2',4'-diols as novel and potent human CHK1 inhibitorsMin Teng, Jinjiang Zhu, Michael D Johnson, et al.Bioorganic & Medicinal Chemistry Letters|September 7, 2010
4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitorsKevin K-C Liu, Shubha Bagrodia, Simon Bailey, et al.Journal of Medicinal Chemistry|March 29, 2011
Optimization of potent, selective, and orally bioavailable pyrrolodinopyrimidine-containing inhibitors of heat shock protein 90. Identification of development candidate 2-amino-4-{4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl}-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamideLuke Zehnder, Michael Bennett, Jerry Meng, et al.Journal of Medicinal Chemistry|December 5, 2025
Discovery of Atirmociclib (PF-07220060): A Potent and Selective CDK4 InhibitorGary M Gallego, Cynthia Palmer, Suvi Orr, et al.Journal of Medicinal Chemistry|June 27, 2018
Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of PainSharan K Bagal, Mark Andrews, Bruce M Bechle, et al.Journal of Medicinal Chemistry|June 10, 2021
Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of CancerKevin D Freeman-Cook, Robert L Hoffman, Douglas C Behenna, et al.Pageof 2