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Journal of Medicinal Chemistry|June 3, 2014
Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEδ prenyl binding siteGunther Zimmermann, Carsten Schultz-Fademrecht, Philipp Küchler, et al.International Journal of Cancer|September 9, 2018
PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRasChristian H Klein, Dina C Truxius, Holger A Vogel, et al.Cell Chemical Biology|April 25, 2017
Covalent Protein Labeling at Glutamic AcidsPablo Martín-Gago, Eyad K Fansa, Michael Winzker, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|November 4, 2016
Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding SiteSandip Murarka, Pablo Martín-Gago, Carsten Schultz-Fademrecht, et al.Angewandte Chemie (International Ed. in English)|January 21, 2017
A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2Pablo Martín-Gago, Eyad K Fansa, Christian H Klein, et al.Nature Communications|April 21, 2016
Identification of pyrazolopyridazinones as PDEδ inhibitorsBjörn Papke, Sandip Murarka, Holger A Vogel, et al.Pageof 5