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Biorxiv : the Preprint Server for Biology|February 9, 2026
The glycine-arginine-rich motif of 53BP1 modulates RNA interactions necessary for its liquid-liquid phase separation during DNA Damage ResponseFederica Terraneo, Marta Ceccon, Oscar Sapkota, et al.Journal of Medicinal Chemistry|December 12, 2013
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activitiesDante Rotili, Stefano Tomassi, Mariarosaria Conte, et al.Chemmedchem|February 1, 2020
Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target ModulationRossella Fioravanti, Annalisa Romanelli, Nicola Mautone, et al.ACS Chemical Neuroscience|August 12, 2025
Uncovering a Mutation-Independent Therapeutic Strategy against Inherited Retinal Diseases: Development of Class I HDAC/LSD1 Hybrid InhibitorsGabriele Carullo, Ilaria Piano, Giulia Salamone, et al.Nature Chemical Biology|July 4, 2024
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1Kwangwoon Lee, Marco Barone, Amanda L Waterbury, et al.European Journal of Medicinal Chemistry|May 7, 2022
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular modelsMartina Menna, Francesco Fiorentino, Biagina Marrocco, et al.European Journal of Medicinal Chemistry|June 4, 2026
Leveraging multitargeting BChE-MAO B inhibitors against microglia-related neuroinflammation: in vitro biological evaluation, structure-activity relationships, drug-like properties, and X-ray crystal complexesMariagrazia Rullo, Gabriella La Spada, Xavier Brazzolotto, et al.Journal of Medicinal Chemistry|February 11, 2017
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity RelationshipPaola Vianello, Luca Sartori, Federica Amigoni, et al.Journal of Medicinal Chemistry|February 11, 2017
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary ExplorationLuca Sartori, Ciro Mercurio, Federica Amigoni, et al.Science Translational Medicine|September 8, 2012
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosisJoão Neres, Florence Pojer, Elisabetta Molteni, et al.Pageof 20