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The Journal of Biological Chemistry|August 25, 2005
SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolismMichael Maceyka, Heidi Sankala, Nitai C Hait, et al.
Journal of Lipid Research|October 14, 2018
Sphingosine kinase 1 activation by estrogen receptor α36 contributes to tamoxifen resistance in breast cancerMelissa A Maczis, Michael Maceyka, Michael R Waters, et al.
The Journal of Biological Chemistry|July 2, 2003
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosisHong Liu, Rachelle E Toman, Sravan K Goparaju, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|January 14, 2017
FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblastsJason Newton, Nitai C Hait, Michael Maceyka, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|February 8, 2023
Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing miceBriana N James, Cynthia Weigel, Christopher D Green, et al.
Journal of Neurochemistry|June 5, 2009
Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNSLaura J Sim-Selley, Paulette B Goforth, Mba U Mba, et al.
The Journal of Allergy and Clinical Immunology|April 6, 2015
Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in miceClement Oyeniran, Jamie L Sturgill, Nitai C Hait, et al.
The Journal of Biological Chemistry|May 10, 2020
Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulationJason Newton, Elisa N D Palladino, Cynthia Weigel, et al.
Nature|June 26, 2010
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2Sergio E Alvarez, Kuzhuvelil B Harikumar, Nitai C Hait, et al.
The Journal of Biological Chemistry|March 8, 2020
Sphingosine-1-phosphate: From insipid lipid to a key regulatorSarah Spiegel
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