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Biomarker Research|October 28, 2020
CCR7 as a novel therapeutic target in t-cell PROLYMPHOCYTIC leukemiaCarlos Cuesta-Mateos, Patricia Fuentes, Alexandra Schrader, et al.
Blood|October 29, 2014
Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3Emma M Haapaniemi, Meri Kaustio, Hanna L M Rajala, et al.
Blood|December 12, 2022
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemiaHeikki Kuusanmäki, Olli Dufva, Markus Vähä-Koskela, et al.
The New England Journal of Medicine|May 18, 2012
Somatic STAT3 mutations in large granular lymphocytic leukemiaHanna L M Koskela, Samuli Eldfors, Pekka Ellonen, et al.
Hemasphere|December 2, 2024
Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphomaDaniel Pölöske, Helena Sorger, Anna Schönbichler, et al.
Blood|June 28, 2024
Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responsesJana von Jan, Sanna Timonen, Till Braun, et al.
Nature Genetics|July 13, 2021
Genome-scale screens identify factors regulating tumor cell responses to natural killer cellsMichal Sheffer, Emily Lowry, Nicky Beelen, et al.
Immunity|December 13, 2023
Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancersOlli Dufva, Sara Gandolfi, Jani Huuhtanen, et al.
Immunity|November 29, 2022
STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulationEtienne Masle-Farquhar, Katherine J L Jackson, Timothy J Peters, et al.
Science Translational Medicine|February 26, 2025
Single-cell analysis of aplastic anemia reveals a convergence of NK and NK-like CD8+ T cells with a disease-associated TCR signatureSofie Lundgren, Jani Huuhtanen, Mikko Keränen, et al.
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