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Journal of Medicinal Chemistry
|
April 29, 2026
Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent Binders
Justin A Caravella, Angela V Toms, Nikolay Sitnikov, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 1, 2011
Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β3 adrenergic receptor agonists
Gregori J Morriello, Harvey R Wendt, Alka Bansal, et al.
Journal of Medicinal Chemistry
|
June 9, 2006
(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Scott D Edmondson, Anthony Mastracchio, Robert J Mathvink, et al.
Journal of Medicinal Chemistry
|
January 21, 2014
Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder
Christopher R Moyes, Richard Berger, Stephen D Goble, et al.
Journal of Medicinal Chemistry
|
July 10, 2023
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279
Silvana Leit, Jeremy Greenwood, Samantha Carriero, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 11, 2017
Discovery of phenyl acetamides as potent and selective GPR119 agonists
Cheng Zhu, Liping Wang, Yuping Zhu, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2016
Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes
Liangqin Guo, Dann L Parker, Yi Zang, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2015
Design of Potent and Orally Active GPR119 Agonists for the Treatment of Type II Diabetes
Ping Liu, Zhiyong Hu, Byron G DuBois, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 3, 2023
Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors
Neil P Grimster, Lakshmaiah Gingipalli, Amber Balazs, et al.
Journal of Medicinal Chemistry
|
December 29, 2015
Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder
Scott D Edmondson, Cheng Zhu, Nam Fung Kar, et al.
Page
of 5
Search research articles
Search
Showing results (31-40 of 44) with videos related to
Sort By:
Page
of 5
Journal of Medicinal Chemistry
|
April 29, 2026
Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent Binders
Justin A Caravella, Angela V Toms, Nikolay Sitnikov, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 1, 2011
Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β3 adrenergic receptor agonists
Gregori J Morriello, Harvey R Wendt, Alka Bansal, et al.
Journal of Medicinal Chemistry
|
June 9, 2006
(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Scott D Edmondson, Anthony Mastracchio, Robert J Mathvink, et al.
Journal of Medicinal Chemistry
|
January 21, 2014
Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder
Christopher R Moyes, Richard Berger, Stephen D Goble, et al.
Journal of Medicinal Chemistry
|
July 10, 2023
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279
Silvana Leit, Jeremy Greenwood, Samantha Carriero, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 11, 2017
Discovery of phenyl acetamides as potent and selective GPR119 agonists
Cheng Zhu, Liping Wang, Yuping Zhu, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2016
Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes
Liangqin Guo, Dann L Parker, Yi Zang, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2015
Design of Potent and Orally Active GPR119 Agonists for the Treatment of Type II Diabetes
Ping Liu, Zhiyong Hu, Byron G DuBois, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 3, 2023
Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors
Neil P Grimster, Lakshmaiah Gingipalli, Amber Balazs, et al.
Journal of Medicinal Chemistry
|
December 29, 2015
Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder
Scott D Edmondson, Cheng Zhu, Nam Fung Kar, et al.
Page
of 5