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Mechanisms of Ageing and Development|February 4, 2014
Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutaseWei Zhao, Bing Xiong Fang, Yu Jie Niu, et al.Plos Genetics|September 21, 2011
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiaeUndine Kruegel, Brett Robison, Thomas Dange, et al.Science Translational Medicine|July 28, 2012
Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survivalFresnida J Ramos, Steven C Chen, Michael G Garelick, et al.Kidney International|November 26, 2018
mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseasesSimon C Johnson, Frank Martinez, Alessandro Bitto, et al.Elife|November 9, 2021
Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeastAlaattin Kaya, Cheryl Zi Jin Phua, Mitchell Lee, et al.Genome Research|March 15, 2008
Quantitative evidence for conserved longevity pathways between divergent eukaryotic speciesErica D Smith, Mitsuhiro Tsuchiya, Lindsay A Fox, et al.Nature Communications|February 2, 2023
FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegansHyo Sub Choi, Ajay Bhat, Marshall B Howington, et al.Frontiers in Genetics|August 11, 2015
Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in miceSimon C Johnson, Melana E Yanos, Alessandro Bitto, et al.Geroscience|May 24, 2024
Fmo induction as a tool to screen for pro-longevity drugsShijiao Huang, Rebecca L Cox, Angela Tuckowski, et al.Genes & Development|July 11, 2015
H3K36 methylation promotes longevity by enhancing transcriptional fidelityPayel Sen, Weiwei Dang, Greg Donahue, et al.Pageof 27