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Molecular Metabolism|November 16, 2025
NLRP3 inhibition by VTX3232 tempers inflammation resulting in reduced body weight, hyperglycemia, and hepatic steatosis in obese male miceJennyfer Bultinck, Shendong Yuan, Ludovico Cantuti-Castelvetri, et al.Biochemistry|June 29, 2005
Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase BMarc Adler, Judi Bryant, Brad Buckman, et al.Bioorganic & Medicinal Chemistry Letters|March 6, 2007
The rational design of inhibitors of nitric oxide formation by inducible nitric oxide synthaseMarc Whitlow, Marc Adler, David Davey, et al.Bioorganic & Medicinal Chemistry Letters|March 21, 2007
1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formationRobert G Wei, Marc Adler, David Davey, et al.Acta Crystallographica. Section D, Biological Crystallography|January 26, 2008
Structures of potent selective peptide mimetics bound to carboxypeptidase BMarc Adler, Brad Buckman, Judi Bryant, et al.Bioorganic & Medicinal Chemistry Letters|December 27, 2006
3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa)Imadul Islam, Judi Bryant, Karen May, et al.Organic Letters|January 11, 2019
Total Synthesis of Covalent Cysteine Protease Inhibitor N-Desmethyl Thalassospiramide C and Crystallographic Evidence for Its Mode of ActionJeremy Fournier, Karen Chen, Artur K Mailyan, et al.Journal of Biomolecular Screening|April 2, 2013
Development of a novel β-secretase binding assay using the AlphaScreen platformZhao Ren, Danny Tam, Ying-Zi Xu, et al.Bioorganic & Medicinal Chemistry Letters|August 26, 2009
Identification of orally bioavailable, non-amidine inhibitors of Urokinase Plasminogen Activator (uPA)Christopher W West, Marc Adler, Danny Arnaiz, et al.Bioorganic & Medicinal Chemistry Letters|April 10, 2018
Reversible, orally available ADP receptor (P2Y<sub>12</sub>) antagonists Part I: Hit to lead processImadul Islam, Shendong Yuan, Robert G Wei, et al.Pageof 3