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The Journal of Pharmacology and Experimental Therapeutics|April 11, 2009
5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological toolKen Shimamura, Hidefumi Kitazawa, Yasuhisa Miyamoto, et al.Journal of Cardiovascular Pharmacology|January 9, 2009
Hemodynamic and cardiac neurotransmitter-releasing effects in conscious dogs of attention- and wake-promoting agents: a comparison of d-amphetamine, atomoxetine, modafinil, and a novel quinazolinone H3 inverse agonistJoseph Lynch, Christopher Regan, Gary Stump, et al.Bioorganic & Medicinal Chemistry|December 31, 2010
Discovery of novel phenylpyridone derivatives as potent and selective MCH1R antagonistsYuji Haga, Sayaka Mizutani, Akira Naya, et al.Bioorganic & Medicinal Chemistry Letters|April 14, 2009
Identification and characterization of a selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R)Masahiko Ito, Toshihiro Sakamoto, Takao Suzuki, et al.American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics|July 27, 2004
Variants of the orexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidityMiles D Thompson, David E Comings, Rashid Abu-Ghazalah, et al.Journal of Medicinal Chemistry|November 4, 2009
Discovery of novel benzoxazinones as potent and orally active long chain fatty acid elongase 6 inhibitorsTakashi Mizutani, Shiho Ishikawa, Tsuyoshi Nagase, et al.Journal of Medicinal Chemistry|July 5, 2008
Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonistsTsuyoshi Nagase, Takashi Mizutani, Shiho Ishikawa, et al.Synapse (New York, N.Y.)|August 12, 2009
Inverse agonist histamine H3 receptor PET tracers labelled with carbon-11 or fluorine-18Terence G Hamill, Nagaaki Sato, Makoto Jitsuoka, et al.Bioorganic & Medicinal Chemistry Letters|May 1, 2009
Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonistsTakao Suzuki, Minoru Moriya, Toshihiro Sakamoto, et al.Bioorganic & Medicinal Chemistry Letters|June 3, 2009
Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activityMinoru Kameda, Kensuke Kobayashi, Hirokatsu Ito, et al.Pageof 7