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Anticancer Research|December 8, 2020
Application of Pharmacometrics of 5-Fluorouracil to Personalized Medicine: A Tool for Predicting Pharmacokinetic-Pharmacodynamic/Toxicodynamic ResponsesShinji Kobuchi, Yukako ItoXenobiotica; the Fate of Foreign Compounds in Biological Systems|November 22, 2022
Predictive marker for exposure-driven haematological toxicity of tegafur-uracil and proposed modified-dosage regimen by pharmacometric approach in ratsShinji Kobuchi, Megumi Matsui, Yukako ItoXenobiotica; the Fate of Foreign Compounds in Biological Systems|April 3, 2019
Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of oxaliplatin for hematological toxicity in ratsShinji Kobuchi, Yosuke Katsuyama, Yukako ItoOncology Letters|January 19, 2019
Association between circadian and chemotherapeutic cycle effects on plasma concentration of 5-fluorouracil and the clinical outcome following definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in patients with esophageal squamous cell carcinomaAkiko Kuwahara, Shinji Kobuchi, Takao TamuraThe Journal of Pharmacology and Experimental Therapeutics|July 15, 2024
Translational Pharmacokinetic-Toxicodynamic Model of Myelosuppression for Dose Optimization in Combination Chemotherapy of Capecitabine and Oxaliplatin from Rats to HumansShinji Kobuchi, Mayuka Arimoto, Yukako ItoEuropean Journal of Drug Metabolism and Pharmacokinetics|November 28, 2016
Population Pharmacokinetic-Pharmacodynamic Modeling of 5-Fluorouracil for Toxicities in RatsShinji Kobuchi, Yukako Ito, Toshiyuki SakaedaCancers|December 24, 2021
Population Pharmacokinetic Model-Based Evaluation of Intact Oxaliplatin in Rats with Acute Kidney InjuryShinji Kobuchi, Miyu Kai, Yukako ItoJournal of Pharmaceutical Sciences|May 14, 2025
Chronopharmacokinetic model analysis of 5-fluorouracil following S-1 administration in rats: comparison with infusion and other prodrugs for chronochemotherapyShinji Kobuchi, Tomoki Satake, Yukako ItoPharmaceutics|February 8, 2020
Semi-Mechanism-Based Pharmacokinetic-Toxicodynamic Model of Oxaliplatin-Induced Acute and Chronic NeuropathyShinji Kobuchi, Risa Shimizu, And Yukako ItoAnticancer Research|August 2, 2019
Assessment of Oxaliplatin-induced Chronic Neuropathy and Anticancer Efficacy Through Pharmacokinetic and Toxicodynamic Evaluation of a Rat Model of Colorectal CancerYukako Ito, Shinji Kobuchi, Waki Takesada, et al.Pageof 7