Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Souers

Showing results (231-240 of 248) with videos related to

Pageof 25
Sort By:
Proceedings of the National Academy of Sciences of the United States of America|February 25, 2018
Coamplification of <i>miR-4728</i> protects <i>HER2</i>-amplified breast cancers from targeted therapyKonstantinos V Floros, Timothy L Lochmann, Bin Hu, et al.
Journal of Medicinal Chemistry|March 31, 2006
Screening for cardiovascular safety: a structure-activity approach for guiding lead selection of melanin concentrating hormone receptor 1 antagonistsPhilip R Kym, Andrew J Souers, Thomas J Campbell, et al.
Cell Death & Disease|January 16, 2015
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)J D Leverson, H Zhang, J Chen, et al.
ACS Medicinal Chemistry Letters|June 20, 2014
Structure-Guided Rescaffolding of Selective Antagonists of BCL-XLMichael F T Koehler, Philippe Bergeron, Edna F Choo, et al.
Bioorganic & Medicinal Chemistry Letters|March 14, 2007
Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activityAndrew S Judd, Andrew J Souers, Dariusz Wodka, et al.
Journal of Medicinal Chemistry|May 2, 2015
Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and SelectivityMilan Bruncko, Le Wang, George S Sheppard, et al.
Journal of Medicinal Chemistry|February 14, 2015
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivityMilan Bruncko, Le Wang, George S Sheppard, et al.
Journal of Medicinal Chemistry|January 11, 2008
Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitorGang Zhao, Andrew J Souers, Martin Voorbach, et al.
Bioorganic & Medicinal Chemistry Letters|December 26, 2006
Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylaminesAndrew J Souers, Rajesh R Iyengar, Andrew S Judd, et al.
Communications Medicine|October 25, 2023
Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patientsJunichiro Yuda, Christine Will, Darren C Phillips, et al.
Pageof 25

Showing results (231-240 of 248) with videos related to

Sort By:
Pageof 25
Proceedings of the National Academy of Sciences of the United States of America|February 25, 2018
Coamplification of <i>miR-4728</i> protects <i>HER2</i>-amplified breast cancers from targeted therapyKonstantinos V Floros, Timothy L Lochmann, Bin Hu, et al.
Journal of Medicinal Chemistry|March 31, 2006
Screening for cardiovascular safety: a structure-activity approach for guiding lead selection of melanin concentrating hormone receptor 1 antagonistsPhilip R Kym, Andrew J Souers, Thomas J Campbell, et al.
Cell Death & Disease|January 16, 2015
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)J D Leverson, H Zhang, J Chen, et al.
ACS Medicinal Chemistry Letters|June 20, 2014
Structure-Guided Rescaffolding of Selective Antagonists of BCL-XLMichael F T Koehler, Philippe Bergeron, Edna F Choo, et al.
Bioorganic & Medicinal Chemistry Letters|March 14, 2007
Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activityAndrew S Judd, Andrew J Souers, Dariusz Wodka, et al.
Journal of Medicinal Chemistry|May 2, 2015
Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and SelectivityMilan Bruncko, Le Wang, George S Sheppard, et al.
Journal of Medicinal Chemistry|February 14, 2015
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivityMilan Bruncko, Le Wang, George S Sheppard, et al.
Journal of Medicinal Chemistry|January 11, 2008
Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitorGang Zhao, Andrew J Souers, Martin Voorbach, et al.
Bioorganic & Medicinal Chemistry Letters|December 26, 2006
Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylaminesAndrew J Souers, Rajesh R Iyengar, Andrew S Judd, et al.
Communications Medicine|October 25, 2023
Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patientsJunichiro Yuda, Christine Will, Darren C Phillips, et al.
Pageof 25