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Bioorganic & Medicinal Chemistry Letters|November 29, 2011
Structure-based design of PDK1 inhibitorsAnders Poulsen, Stéphanie Blanchard, Chang Kai Soh, et al.Journal of Computer-Aided Molecular Design|April 25, 2012
Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3)Anders Poulsen, Anthony William, Stéphanie Blanchard, et al.Journal of Chemical Information and Modeling|October 16, 2014
Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602Anders Poulsen, Harish Nagaraj, Angeline Lee, et al.Journal of Molecular Modeling|July 24, 2012
Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3)Anders Poulsen, Anthony William, Stéphanie Blanchard, et al.Journal of Medicinal Chemistry|February 6, 2004
Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic propertiesStéphanie Blanchard, Ivan Rodriguez, Christelle Tardy, et al.Journal of Computer-Aided Molecular Design|June 25, 2008
Structure-based design of Aurora A & B inhibitorsAnders Poulsen, Anthony William, Angeline Lee, et al.Bioorganic & Medicinal Chemistry Letters|May 18, 2012
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDK1 inhibitors discovered by fragment-based screeningAngeline C-H Lee, Pondy Murugappan Ramanujulu, Anders Poulsen, et al.Bioorganic & Medicinal Chemistry Letters|March 23, 2012
2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1Stéphanie Blanchard, Chang Kai Soh, Chai Ping Lee, et al.Bioorganic & Medicinal Chemistry Letters|March 27, 2010
Synthesis and evaluation of alkenyl indazoles as selective Aurora kinase inhibitorsStéphanie Blanchard, Anthony D William, Angeline C-H Lee, et al.Journal of Medicinal Chemistry|December 14, 2011
Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancerAnthony D William, Angeline C-H Lee, Kee Chuan Goh, et al.Pageof 2