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Nucleic Acids Research|September 22, 2018
COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathwaysXue-Hai Liang, Hong Sun, Joshua G Nichols, et al.Journal of Multimorbidity and Comorbidity|June 7, 2022
Multimorbidity and mortality: A data science perspectiveKien Wei Siah, Chi Heem Wong, Jerry Gupta, et al.Drug Safety|May 17, 2022
Identifying and Mitigating Potential Biases in Predicting Drug ApprovalsQingyang Xu, Elaheh Ahmadi, Alexander Amini, et al.JAMA Oncology|April 19, 2017
Use of Bayesian Decision Analysis to Minimize Harm in Patient-Centered Randomized Clinical Trials in OncologyVahid Montazerhodjat, Shomesh E Chaudhuri, Daniel J Sargent, et al.JCO Clinical Cancer Informatics|September 21, 2019
Machine-Learning and Stochastic Tumor Growth Models for Predicting Outcomes in Patients With Advanced Non-Small-Cell Lung CancerKien Wei Siah, Sean Khozin, Chi Heem Wong, et al.ACS Medicinal Chemistry Letters|June 18, 2021
Site-specific Incorporation of 2',5'-Linked Nucleic Acids Enhances Therapeutic Profile of Antisense OligonucleotidesThazha P Prakash, Jinghua Yu, Wen Shen, et al.Nucleic Acid Therapeutics|July 21, 2022
The Combination of Mesyl-Phosphoramidate Inter-Nucleotide Linkages and 2'-O-Methyl in Selected Positions in the Antisense Oligonucleotide Enhances the Performance of RNaseH1 Active PS-ASOsLingdi Zhang, Xue-Hai Liang, Cheryl Li De Hoyos, et al.Nucleic Acids Research|July 17, 2025
Splice-modulating antisense oligonucleotides targeting a pathogenic intronic variant in adult polyglucosan body disease correct mis-splicing and restore enzyme activity in patient cellsRia Thomas, Emily Miyoshi, Hasan O Akman, et al.Nucleic Acid Therapeutics|November 30, 2017
The Effects of 2'-O-Methoxyethyl Oligonucleotides on Renal Function in HumansStanley T Crooke, Brenda F Baker, Nguyen C Pham, et al.Nucleic Acids Research|May 1, 2016
Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver functionWalt F Lima, Heather M Murray, Sagar S Damle, et al.Pageof 17