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Stanley T Crooke

Showing results (81-90 of 122) with videos related to

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Nucleic Acids Research|March 6, 2016
Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activityXue-Hai Liang, Wen Shen, Hong Sun, et al.
The Journal of Biological Chemistry|December 11, 2002
Human RNase H1 activity is regulated by a unique redox switch formed between adjacent cysteinesWalt F Lima, Hongjiang Wu, Josh G Nichols, et al.
Nucleic Acid Therapeutics|January 16, 2024
Safety and Tolerability of GalNAc<sub>3</sub>-Conjugated Antisense Drugs Compared to the Same-Sequence 2'-<i>O</i>-Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial DataBrenda F Baker, Shuting Xia, Wesley Partridge, et al.
JCI Insight|March 20, 2025
A toxic gain-of-function variant in MAPK8IP3 provides insights into JIP3 cellular rolesWei Zhang, Swapnil Mittal, Ria Thomas, et al.
Journal of Lipid Research|January 24, 2007
Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic miceMark J Graham, Kristina M Lemonidis, Charles P Whipple, et al.
Nucleic Acids Research|December 17, 2019
Golgi-endosome transport mediated by M6PR facilitates release of antisense oligonucleotides from endosomesXue-Hai Liang, Hong Sun, Chih-Wei Hsu, et al.
Nucleic Acid Therapeutics|December 21, 2018
Integrated Assessment of the Clinical Performance of GalNAc<sub>3</sub>-Conjugated 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides: I. Human Volunteer ExperienceStanley T Crooke, Brenda F Baker, Shuting Xia, et al.
The Journal of Biological Chemistry|June 19, 2004
Structural requirements at the catalytic site of the heteroduplex substrate for human RNase H1 catalysisWalt F Lima, Josh G Nichols, Hongjiang Wu, et al.
Molecular Pharmacology|October 10, 2006
Human RNase H1 discriminates between subtle variations in the structure of the heteroduplex substrateWalt F Lima, John B Rose, Josh G Nichols, et al.
Nucleic Acids Research|September 22, 2018
COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathwaysXue-Hai Liang, Hong Sun, Joshua G Nichols, et al.
Pageof 13

Showing results (81-90 of 122) with videos related to

Sort By:
Pageof 13
Nucleic Acids Research|March 6, 2016
Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activityXue-Hai Liang, Wen Shen, Hong Sun, et al.
The Journal of Biological Chemistry|December 11, 2002
Human RNase H1 activity is regulated by a unique redox switch formed between adjacent cysteinesWalt F Lima, Hongjiang Wu, Josh G Nichols, et al.
Nucleic Acid Therapeutics|January 16, 2024
Safety and Tolerability of GalNAc<sub>3</sub>-Conjugated Antisense Drugs Compared to the Same-Sequence 2'-<i>O</i>-Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial DataBrenda F Baker, Shuting Xia, Wesley Partridge, et al.
JCI Insight|March 20, 2025
A toxic gain-of-function variant in MAPK8IP3 provides insights into JIP3 cellular rolesWei Zhang, Swapnil Mittal, Ria Thomas, et al.
Journal of Lipid Research|January 24, 2007
Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic miceMark J Graham, Kristina M Lemonidis, Charles P Whipple, et al.
Nucleic Acids Research|December 17, 2019
Golgi-endosome transport mediated by M6PR facilitates release of antisense oligonucleotides from endosomesXue-Hai Liang, Hong Sun, Chih-Wei Hsu, et al.
Nucleic Acid Therapeutics|December 21, 2018
Integrated Assessment of the Clinical Performance of GalNAc<sub>3</sub>-Conjugated 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides: I. Human Volunteer ExperienceStanley T Crooke, Brenda F Baker, Shuting Xia, et al.
The Journal of Biological Chemistry|June 19, 2004
Structural requirements at the catalytic site of the heteroduplex substrate for human RNase H1 catalysisWalt F Lima, Josh G Nichols, Hongjiang Wu, et al.
Molecular Pharmacology|October 10, 2006
Human RNase H1 discriminates between subtle variations in the structure of the heteroduplex substrateWalt F Lima, John B Rose, Josh G Nichols, et al.
Nucleic Acids Research|September 22, 2018
COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathwaysXue-Hai Liang, Hong Sun, Joshua G Nichols, et al.
Pageof 13