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Lab on a Chip|February 2, 2022
Exploration and application of a liver-on-a-chip device in combination with modelling and simulation for quantitative drug metabolism studiesLuca Docci, Nicolò Milani, Thomas Ramp, et al.
Frontiers in Microbiology|October 26, 2019
Pseudomonas aeruginosa-Derived Volatile Sulfur Compounds Promote Distal Aspergillus fumigatus Growth and a Synergistic Pathogen-Pathogen Interaction That Increases Pathogenicity in Co-infectionJennifer Scott, Monica Sueiro-Olivares, Waqar Ahmed, et al.
The AAPS Journal|October 7, 2022
Preclinical InVivo Data Integrated in a Modeling Network Informs a Refined Clinical Strategy for a CD3 T-Cell Bispecific in Combination with Anti-PD-L1Javier Sánchez, Valeria Nicolini, Linda Fahrni, et al.
Lab on a Chip|January 15, 2020
Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterizationStephen Fowler, Wen Li Kelly Chen, David B Duignan, et al.
BMJ Open|October 26, 2024
Rapid Access Diagnostics for Asthma (RADicA): protocol for a prospective cohort study to determine the optimum series of investigations to diagnose asthma using conventional and novel testsClare S Murray, Stephen Fowler, Sarah Drake, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 8, 2021
Addressing Today's Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier RisdiplamStephen Fowler, Andreas Brink, Yumi Cleary, et al.
Investigational New Drugs|August 21, 2021
In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK)Georgina Meneses-Lorente, Stephen Fowler, Elena Guerini, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|October 29, 2014
In vitro profiling of the metabolism and drug-drug interaction of tofogliflozin, a potent and highly specific sodium-glucose co-transporter 2 inhibitor, using human liver microsomes, human hepatocytes, and recombinant human CYPMizuki Yamane, Kosuke Kawashima, Koji Yamaguchi, et al.
The AAPS Journal|January 5, 2017
Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects ModelingNicole A Kratochwil, Christophe Meille, Stephen Fowler, et al.
The Journal of Allergy and Clinical Immunology. in Practice|March 7, 2020
Effectiveness of myAirCoach: A mHealth Self-Management System in AsthmaRishi J Khusial, Persijn J Honkoop, Omar Usmani, et al.
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