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Journal of the American Chemical Society|November 30, 2006
FEP-guided selection of bicyclic heterocycles in lead optimization for non-nucleoside inhibitors of HIV-1 reverse transcriptaseJoseph T Kim, Andrew D Hamilton, Christopher M Bailey, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 4, 2011
Combination of farnesyltransferase and Akt inhibitors is synergistic in breast cancer cells and causes significant breast tumor regression in ErbB2 transgenic miceMaria E Balasis, Kara D Forinash, Y Ann Chen, et al.
Chemmedchem|August 6, 2020
Antimicrobial Peptide Mimetics Based on a Diphenylacetylene Scaffold: Synthesis, Conformational Analysis, and ActivityHayden Peacock, Sónia Troeira Henriques, Aurélie H Benfield, et al.
Chemmedchem|June 26, 2020
Rationally Designed Polypharmacology: α-Helix Mimetics as Dual Inhibitors of the Oncoproteins Mcl-1 and HDM2Ivie L Conlon, Brandon Drennen, Maryanna E Lanning, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2012
Pharmacophore identification of c-Myc inhibitor 10074-G5Jeremy L Yap, Huabo Wang, Angela Hu, et al.
Molecular Cell|April 24, 2018
Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to ChromatinChul-Hwan Lee, Jia-Ray Yu, Sunil Kumar, et al.
Organic Letters|June 15, 2013
Amphipathic α-helix mimetics based on a 1,2-diphenylacetylene scaffoldKwan-Young Jung, Kenno Vanommeslaeghe, Maryanna E Lanning, et al.
Chemmedchem|February 5, 2016
Structural Re-engineering of the α-Helix Mimetic JY-1-106 into Small Molecules: Disruption of the Mcl-1-Bak-BH3 Protein-Protein Interaction with 2,6-Di-Substituted NicotinatesBrandon Drennen, Jacob A Scheenstra, Jeremy L Yap, et al.
Bioorganic & Medicinal Chemistry Letters|March 6, 2007
Isoform selective inhibition of STAT1 or STAT3 homo-dimerization via peptidomimetic probes: structural recognition of STAT SH2 domainsPatrick T Gunning, William P Katt, Matthew Glenn, et al.
Theranostics|August 2, 2021
Orthogonal targeting of osteoclasts and myeloma cells for radionuclide stimulated dynamic therapy induces multidimensional cell death pathwaysAlexander Zheleznyak, Matthew Mixdorf, Lynne Marsala, et al.
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