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Molecular Cancer Therapeutics|March 18, 2004
Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesisFlorence I Raynaud, Peter M Fischer, Bernard P Nutley, et al.
Cancer Research|June 3, 2005
Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factorsNoan-Minh Chau, Paul Rogers, Wynne Aherne, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|January 21, 2010
Targeting the Hsp90 chaperone: synthesis of novel resorcylic acid macrolactone inhibitors of Hsp90James E H Day, Swee Y Sharp, Martin G Rowlands, et al.
Current Opinion in Pharmacology|August 30, 2008
Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promisesTimothy A Yap, Michelle D Garrett, Mike I Walton, et al.
Oncotarget|July 16, 2013
Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signalingGrazia Saturno, Melanie Valenti, Alexis De Haven Brandon, et al.
Organic & Biomolecular Chemistry|April 2, 2016
Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolinesAlpa Patel, Swee Y Sharp, Katelan Hall, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|July 13, 2002
Validation of the fluorinated 2-nitroimidazole SR-4554 as a noninvasive hypoxia marker detected by magnetic resonance spectroscopyBeatrice M Seddon, Ross J Maxwell, Davina J Honess, et al.
Cancer Research|May 4, 2013
MEK1/2 inhibition decreases lactate in BRAF-driven human cancer cellsMaria Falck Miniotis, Vaitha Arunan, Thomas R Eykyn, et al.
Oncotarget|November 2, 2010
Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibitionMounia Beloueche-Babari, Vaitha Arunan, L Elizabeth Jackson, et al.
Chemical Research in Toxicology|October 20, 2007
AHR- and DNA-damage-mediated gene expression responses induced by benzo(a)pyrene in human cell linesSarah L Hockley, Volker M Arlt, Daniel Brewer, et al.
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