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ACS Medicinal Chemistry Letters
|
April 16, 2020
New 8-Nitroquinolinone Derivative Displaying Submicromolar <i>in Vitro</i> Activities against Both <i>Trypanosoma brucei</i> and <i>cruzi</i>
Julien Pedron, Clotilde Boudot, Jean-Yves Brossas, et al.
Journal of Medicinal Chemistry
|
June 21, 2023
Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues
Laura A T Cleghorn, Richard J Wall, Sébastien Albrecht, et al.
European Journal of Medicinal Chemistry
|
August 16, 2020
Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties
Cyril Fersing, Clotilde Boudot, Romain Paoli-Lombardo, et al.
Trends in Parasitology
|
March 2, 2021
MalDA, Accelerating Malaria Drug Discovery
Tuo Yang, Sabine Ottilie, Eva S Istvan, et al.
European Journal of Medicinal Chemistry
|
July 12, 2020
8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi
Cyril Fersing, Clotilde Boudot, Caroline Castera-Ducros, et al.
Science Translational Medicine
|
July 9, 2025
Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease
Lindsay B Tulloch, Hugh Tawell, Annie E Taylor, et al.
Journal of Medicinal Chemistry
|
March 18, 2022
Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis
Alasdair Smith, Richard J Wall, Stephen Patterson, et al.
Science Translational Medicine
|
December 13, 2023
Short-course combination treatment for experimental chronic Chagas disease
Silvia González, Richard J Wall, John Thomas, et al.
Nature Communications
|
March 17, 2023
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation
Selina Bopp, Charisse Flerida A Pasaje, Robert L Summers, et al.
Nature
|
July 27, 2018
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis
Susan Wyllie, Michael Thomas, Stephen Patterson, et al.
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Search research articles
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Showing results (81-90 of 94) with videos related to
Sort By:
Page
of 10
ACS Medicinal Chemistry Letters
|
April 16, 2020
New 8-Nitroquinolinone Derivative Displaying Submicromolar <i>in Vitro</i> Activities against Both <i>Trypanosoma brucei</i> and <i>cruzi</i>
Julien Pedron, Clotilde Boudot, Jean-Yves Brossas, et al.
Journal of Medicinal Chemistry
|
June 21, 2023
Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues
Laura A T Cleghorn, Richard J Wall, Sébastien Albrecht, et al.
European Journal of Medicinal Chemistry
|
August 16, 2020
Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties
Cyril Fersing, Clotilde Boudot, Romain Paoli-Lombardo, et al.
Trends in Parasitology
|
March 2, 2021
MalDA, Accelerating Malaria Drug Discovery
Tuo Yang, Sabine Ottilie, Eva S Istvan, et al.
European Journal of Medicinal Chemistry
|
July 12, 2020
8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi
Cyril Fersing, Clotilde Boudot, Caroline Castera-Ducros, et al.
Science Translational Medicine
|
July 9, 2025
Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease
Lindsay B Tulloch, Hugh Tawell, Annie E Taylor, et al.
Journal of Medicinal Chemistry
|
March 18, 2022
Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis
Alasdair Smith, Richard J Wall, Stephen Patterson, et al.
Science Translational Medicine
|
December 13, 2023
Short-course combination treatment for experimental chronic Chagas disease
Silvia González, Richard J Wall, John Thomas, et al.
Nature Communications
|
March 17, 2023
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation
Selina Bopp, Charisse Flerida A Pasaje, Robert L Summers, et al.
Nature
|
July 27, 2018
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis
Susan Wyllie, Michael Thomas, Stephen Patterson, et al.
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of 10