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Suvi T M Orr

Showing results (1-10 of 14) with videos related to

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Organic Letters|September 6, 2011
Novel approach to the lundurine alkaloids: synthesis of the tetracyclic coreSuvi T M Orr, Jianhua Tian, Meike Niggemann, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 24, 2013
Reactive metabolite trapping studies on imidazo- and 2-methylimidazo[2,1-b]thiazole-based inverse agonists of the ghrelin receptorAmit S Kalgutkar, Tim F Ryder, Gregory S Walker, et al.
Plos One|November 15, 2018
Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugsHao Sun, David W Piotrowski, Suvi T M Orr, et al.
ACS Medicinal Chemistry Letters|February 21, 2015
Evaluation and synthesis of polar aryl- and heteroaryl spiroazetidine-piperidine acetamides as ghrelin inverse agonistsSuvi T M Orr, Ramsay Beveridge, Samit K Bhattacharya, et al.
ACS Medicinal Chemistry Letters|December 1, 2015
Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic TreatmentMark Ammirati, Scott W Bagley, Samit K Bhattacharya, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical CandidateSamit K Bhattacharya, Kim Andrews, Ramsay Beveridge, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 AgonistsDavid W Piotrowski, Kentaro Futatsugi, Joseph S Warmus, et al.
Journal of Medicinal Chemistry|September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Bioorganic & Medicinal Chemistry Letters|August 20, 2013
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptorKim F McClure, Margaret Jackson, Kimberly O Cameron, et al.
Journal of Medicinal Chemistry|October 29, 2015
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular DiseasesRoger B Ruggeri, Leonard Buckbinder, Scott W Bagley, et al.
Pageof 2

Showing results (1-10 of 14) with videos related to

Sort By:
Pageof 2
Organic Letters|September 6, 2011
Novel approach to the lundurine alkaloids: synthesis of the tetracyclic coreSuvi T M Orr, Jianhua Tian, Meike Niggemann, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 24, 2013
Reactive metabolite trapping studies on imidazo- and 2-methylimidazo[2,1-b]thiazole-based inverse agonists of the ghrelin receptorAmit S Kalgutkar, Tim F Ryder, Gregory S Walker, et al.
Plos One|November 15, 2018
Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugsHao Sun, David W Piotrowski, Suvi T M Orr, et al.
ACS Medicinal Chemistry Letters|February 21, 2015
Evaluation and synthesis of polar aryl- and heteroaryl spiroazetidine-piperidine acetamides as ghrelin inverse agonistsSuvi T M Orr, Ramsay Beveridge, Samit K Bhattacharya, et al.
ACS Medicinal Chemistry Letters|December 1, 2015
Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic TreatmentMark Ammirati, Scott W Bagley, Samit K Bhattacharya, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical CandidateSamit K Bhattacharya, Kim Andrews, Ramsay Beveridge, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 AgonistsDavid W Piotrowski, Kentaro Futatsugi, Joseph S Warmus, et al.
Journal of Medicinal Chemistry|September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Bioorganic & Medicinal Chemistry Letters|August 20, 2013
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptorKim F McClure, Margaret Jackson, Kimberly O Cameron, et al.
Journal of Medicinal Chemistry|October 29, 2015
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular DiseasesRoger B Ruggeri, Leonard Buckbinder, Scott W Bagley, et al.
Pageof 2