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Bioorganic & Medicinal Chemistry Letters
|
February 17, 2005
Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction
Ian R Hardcastle, Shafiq U Ahmed, Helen Atkins, et al.
Journal of Medicinal Chemistry
|
March 21, 2007
Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase
Jonathan J Hollick, Laurent J M Rigoreau, Celine Cano-Soumillac, et al.
Journal of Medicinal Chemistry
|
October 16, 2004
Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase
Jayashree G Tikhe, Stephen E Webber, Zdenek Hostomsky, et al.
Journal of Molecular Microbiology and Biotechnology
|
March 10, 2016
Anaerobic Microbial Degradation of Hydrocarbons: From Enzymatic Reactions to the Environment
Ralf Rabus, Matthias Boll, Johann Heider, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines
Christopher R Coxon, Elizabeth Anscombe, Suzannah J Harnor, et al.
Journal of Medicinal Chemistry
|
February 15, 2011
Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potency
Ian R Hardcastle, Junfeng Liu, Eric Valeur, et al.
Cell Systems
|
September 11, 2025
Chemotherapy modulation by a cancer-associated microbiota metabolite
Daniel Martinez-Martinez, Tanara V Peres, Kristin Gehling, et al.
Journal of Medicinal Chemistry
|
November 1, 2002
Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: design, synthesis, and X-ray cocrystal structure
Stacie S Canan Koch, Lars H Thoresen, Jayashree G Tikhe, et al.
Journal of Medicinal Chemistry
|
April 25, 2022
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor
Duncan C Miller, Tristan Reuillon, Lauren Molyneux, et al.
European Journal of Medicinal Chemistry
|
June 19, 2019
Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4
Stephanie M Myers, Duncan C Miller, Lauren Molyneux, et al.
Page
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Search research articles
Search
Showing results (181-190 of 192) with videos related to
Sort By:
Page
of 20
Bioorganic & Medicinal Chemistry Letters
|
February 17, 2005
Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction
Ian R Hardcastle, Shafiq U Ahmed, Helen Atkins, et al.
Journal of Medicinal Chemistry
|
March 21, 2007
Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase
Jonathan J Hollick, Laurent J M Rigoreau, Celine Cano-Soumillac, et al.
Journal of Medicinal Chemistry
|
October 16, 2004
Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase
Jayashree G Tikhe, Stephen E Webber, Zdenek Hostomsky, et al.
Journal of Molecular Microbiology and Biotechnology
|
March 10, 2016
Anaerobic Microbial Degradation of Hydrocarbons: From Enzymatic Reactions to the Environment
Ralf Rabus, Matthias Boll, Johann Heider, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines
Christopher R Coxon, Elizabeth Anscombe, Suzannah J Harnor, et al.
Journal of Medicinal Chemistry
|
February 15, 2011
Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potency
Ian R Hardcastle, Junfeng Liu, Eric Valeur, et al.
Cell Systems
|
September 11, 2025
Chemotherapy modulation by a cancer-associated microbiota metabolite
Daniel Martinez-Martinez, Tanara V Peres, Kristin Gehling, et al.
Journal of Medicinal Chemistry
|
November 1, 2002
Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: design, synthesis, and X-ray cocrystal structure
Stacie S Canan Koch, Lars H Thoresen, Jayashree G Tikhe, et al.
Journal of Medicinal Chemistry
|
April 25, 2022
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor
Duncan C Miller, Tristan Reuillon, Lauren Molyneux, et al.
European Journal of Medicinal Chemistry
|
June 19, 2019
Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4
Stephanie M Myers, Duncan C Miller, Lauren Molyneux, et al.
Page
of 20