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Seminars in Cell & Developmental Biology|March 16, 2020
Structure-activity relationship of presenilin in γ-secretase-mediated intramembrane cleavageTetsuo Cai, Taisuke TomitaJournal of Biochemistry|March 19, 2021
Sequential conformational changes in transmembrane domains of presenilin 1 in Aβ42 downregulationTetsuo Cai, Taisuke TomitaBio-Protocol|August 16, 2021
Structural Analysis of Target Protein by Substituted Cysteine Accessibility MethodTetsuo Cai, Taisuke TomitaThe Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 10, 2017
Activation of γ-Secretase Trimming Activity by Topological Changes of Transmembrane Domain 1 of Presenilin 1Tetsuo Cai, Masahiro Yonaga, Taisuke TomitaJournal of Biochemistry|December 10, 2019
Histidine 131 in presenilin 1 is the pH-sensitive residue that causes the increase in Aβ42 level in acidic pHTetsuo Cai, Aki Hatano, Kunihiko Kanatsu, et al.Journal of Biochemistry|October 6, 2018
Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimmingSo Imai, Tetsuo Cai, Chika Yoshida, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|September 19, 2019
Conformational Dynamics of Transmembrane Domain 3 of Presenilin 1 Is Associated with the Trimming Activity of γ-SecretaseTetsuo Cai, Kanan Morishima, Shizuka Takagi-Niidome, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|January 29, 2016
Conformational Changes in Transmembrane Domain 4 of Presenilin 1 Are Associated with Altered Amyloid-β 42 ProductionAya Tominaga, Tetsuo Cai, Shizuka Takagi-Niidome, et al.The Journal of Biological Chemistry|November 13, 2015
Suppressor Mutations for Presenilin 1 Familial Alzheimer Disease Mutants Modulate γ-Secretase ActivitiesEugene Futai, Satoko Osawa, Tetsuo Cai, et al.Eneuro|February 20, 2021
Flexible and Accurate Substrate Processing with Distinct Presenilin/γ-Secretases in Human Cortical NeuronsHirotaka Watanabe, Kent Imaizumi, Tetsuo Cai, et al.Pageof 2