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Pharmacology & Therapeutics
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October 8, 2017
The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: Special focus on I<sub>K1</sub>
Birgit Goversen, Marcel A G van der Heyden, Toon A B van Veen, et al.
Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
|
May 26, 2020
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments
Chon Lok Lei, Michael Clerx, Dominic G Whittaker, et al.
Pharmacology & Therapeutics
|
April 6, 2013
Cardiac ion channel trafficking defects and drugs
Kathy C G de Git, Teun P de Boer, Marc A Vos, et al.
Frontiers in Physiology
|
February 8, 2024
Recording ten-fold larger I<sub>Kr</sub> conductances with automated patch clamping using equimolar Cs<sup>+</sup> solutions
Meye Bloothooft, Bente Verbruggen, Fitzwilliam Seibertz, et al.
Progress in Biophysics and Molecular Biology
|
May 11, 2018
Cardiac Ca<sup>2+</sup> signalling in zebrafish: Translation of findings to man
Chantal J M van Opbergen, Stephanie M van der Voorn, Marc A Vos, et al.
European Journal of Pharmacology
|
December 1, 2010
Inhibition of lysosomal degradation rescues pentamidine-mediated decreases of K(IR)2.1 ion channel expression but not that of K(v)11.1
Lukas Nalos, Teun P de Boer, Marien J C Houtman, et al.
Frontiers in Physiology
|
February 7, 2018
A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of I<sub>k1</sub> Ion Channels in Real-Time
Birgit Goversen, Nadine Becker, Sonja Stoelzle-Feix, et al.
Wellcome Open Research
|
November 22, 2021
A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer
Chon Lok Lei, Alan Fabbri, Dominic G Whittaker, et al.
Journal of Molecular and Cellular Cardiology
|
February 23, 2012
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
Malin K B Jonsson, Marc A Vos, Gary R Mirams, et al.
Progress in Biophysics and Molecular Biology
|
March 4, 2019
The influence of hERG1a and hERG1b isoforms on drug safety screening in iPSC-CMs
Birgit Goversen, Malin Kb Jonsson, Nikki Hl van den Heuvel, et al.
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of 7
Search research articles
Search
Showing results (11-20 of 61) with videos related to
Sort By:
Page
of 7
Pharmacology & Therapeutics
|
October 8, 2017
The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: Special focus on I<sub>K1</sub>
Birgit Goversen, Marcel A G van der Heyden, Toon A B van Veen, et al.
Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
|
May 26, 2020
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments
Chon Lok Lei, Michael Clerx, Dominic G Whittaker, et al.
Pharmacology & Therapeutics
|
April 6, 2013
Cardiac ion channel trafficking defects and drugs
Kathy C G de Git, Teun P de Boer, Marc A Vos, et al.
Frontiers in Physiology
|
February 8, 2024
Recording ten-fold larger I<sub>Kr</sub> conductances with automated patch clamping using equimolar Cs<sup>+</sup> solutions
Meye Bloothooft, Bente Verbruggen, Fitzwilliam Seibertz, et al.
Progress in Biophysics and Molecular Biology
|
May 11, 2018
Cardiac Ca<sup>2+</sup> signalling in zebrafish: Translation of findings to man
Chantal J M van Opbergen, Stephanie M van der Voorn, Marc A Vos, et al.
European Journal of Pharmacology
|
December 1, 2010
Inhibition of lysosomal degradation rescues pentamidine-mediated decreases of K(IR)2.1 ion channel expression but not that of K(v)11.1
Lukas Nalos, Teun P de Boer, Marien J C Houtman, et al.
Frontiers in Physiology
|
February 7, 2018
A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of I<sub>k1</sub> Ion Channels in Real-Time
Birgit Goversen, Nadine Becker, Sonja Stoelzle-Feix, et al.
Wellcome Open Research
|
November 22, 2021
A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer
Chon Lok Lei, Alan Fabbri, Dominic G Whittaker, et al.
Journal of Molecular and Cellular Cardiology
|
February 23, 2012
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
Malin K B Jonsson, Marc A Vos, Gary R Mirams, et al.
Progress in Biophysics and Molecular Biology
|
March 4, 2019
The influence of hERG1a and hERG1b isoforms on drug safety screening in iPSC-CMs
Birgit Goversen, Malin Kb Jonsson, Nikki Hl van den Heuvel, et al.
Page
of 7