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Thierry O Fischmann

Showing results (1-10 of 28) with videos related to

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ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hinge Binding ModeXiaohua Huang, Cliff C Cheng, Thierry O Fischmann, et al.
FEBS Letters|November 25, 2010
Structural basis of CX-4945 binding to human protein kinase CK2Andrew D Ferguson, Payal R Sheth, Andrea D Basso, et al.
RNA Biology|August 4, 2016
Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitchJohn A Howe, Li Xiao, Thierry O Fischmann, et al.
Bioorganic & Medicinal Chemistry Letters|April 17, 2013
Potency switch between CHK1 and MK2: discovery of imidazo[1,2-a]pyrazine- and imidazo[1,2-c]pyrimidine-based kinase inhibitorsZhaoyang Meng, Jeffrey P Ciavarri, Andrew McRiner, et al.
Bioorganic & Medicinal Chemistry Letters|October 5, 2013
Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: a template-based approachMichael P Dwyer, Kartik Keertikar, Kamil Paruch, et al.
NPJ Microgravity|December 10, 2019
Pembrolizumab microgravity crystallization experimentationPaul Reichert, Winifred Prosise, Thierry O Fischmann, et al.
Biochemistry|January 24, 2009
Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitorsThierry O Fischmann, Catherine K Smith, Todd W Mayhood, et al.
ACS Medicinal Chemistry Letters|August 20, 2015
Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 InhibitorsW Michael Seganish, Thierry O Fischmann, Brad Sherborne, et al.
Bioorganic & Medicinal Chemistry Letters|November 25, 2010
Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: a template-based approach--part 2Marc Labroli, Kamil Paruch, Michael P Dwyer, et al.
Bioorganic & Medicinal Chemistry Letters|April 15, 2015
Discovery and hit-to-lead optimization of 2,6-diaminopyrimidine inhibitors of interleukin-1 receptor-associated kinase 4William T McElroy, W Michael Seganish, R Jason Herr, et al.
Pageof 3

Showing results (1-10 of 28) with videos related to

Sort By:
Pageof 3
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hinge Binding ModeXiaohua Huang, Cliff C Cheng, Thierry O Fischmann, et al.
FEBS Letters|November 25, 2010
Structural basis of CX-4945 binding to human protein kinase CK2Andrew D Ferguson, Payal R Sheth, Andrea D Basso, et al.
RNA Biology|August 4, 2016
Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitchJohn A Howe, Li Xiao, Thierry O Fischmann, et al.
Bioorganic & Medicinal Chemistry Letters|April 17, 2013
Potency switch between CHK1 and MK2: discovery of imidazo[1,2-a]pyrazine- and imidazo[1,2-c]pyrimidine-based kinase inhibitorsZhaoyang Meng, Jeffrey P Ciavarri, Andrew McRiner, et al.
Bioorganic & Medicinal Chemistry Letters|October 5, 2013
Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: a template-based approachMichael P Dwyer, Kartik Keertikar, Kamil Paruch, et al.
NPJ Microgravity|December 10, 2019
Pembrolizumab microgravity crystallization experimentationPaul Reichert, Winifred Prosise, Thierry O Fischmann, et al.
Biochemistry|January 24, 2009
Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitorsThierry O Fischmann, Catherine K Smith, Todd W Mayhood, et al.
ACS Medicinal Chemistry Letters|August 20, 2015
Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 InhibitorsW Michael Seganish, Thierry O Fischmann, Brad Sherborne, et al.
Bioorganic & Medicinal Chemistry Letters|November 25, 2010
Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: a template-based approach--part 2Marc Labroli, Kamil Paruch, Michael P Dwyer, et al.
Bioorganic & Medicinal Chemistry Letters|April 15, 2015
Discovery and hit-to-lead optimization of 2,6-diaminopyrimidine inhibitors of interleukin-1 receptor-associated kinase 4William T McElroy, W Michael Seganish, R Jason Herr, et al.
Pageof 3