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Journal of Medicinal Chemistry|August 19, 2005
A molecular target for suppression of the evolution of antibiotic resistance: inhibition of the Escherichia coli RecA protein by N(6)-(1-naphthyl)-ADPAndrew M Lee, Christian T Ross, Bu-Bing Zeng, et al.Journal of Medicinal Chemistry|October 12, 2010
Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compoundsDmitri Kireev, Tim J Wigle, Jacqueline Norris-Drouin, et al.Chemistry & Biology|July 28, 2010
Accessing protein methyltransferase and demethylase enzymology using microfluidic capillary electrophoresisTim J Wigle, Laurel M Provencher, Jacqueline L Norris, et al.Nature Chemical Biology|January 17, 2012
Evidence for dynamics in proteins as a mechanism for ligand dissociationMary J Carroll, Randall V Mauldin, Anna V Gromova, et al.Journal of Biomolecular Screening|December 17, 2009
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteinsTim J Wigle, J Martin Herold, Guillermo A Senisterra, et al.FEBS Letters|August 23, 2011
The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation statesTim J Wigle, Sarah K Knutson, Lei Jin, et al.The Biochemical Journal|May 18, 2013
Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Lys²⁷ methylation by human polycomb repressive complex 2 and vSETBrooke M Swalm, Kenneth K Hallenbeck, Christina R Majer, et al.Journal of Biomolecular Screening|September 28, 2012
Inhibitors of Streptococcus pneumoniae surface endonuclease EndA discovered by high-throughput screening using a PicoGreen fluorescence assayEliza J R Peterson, Dmitri Kireev, Andrea F Moon, et al.Biochemistry|January 28, 2016
Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IPAravind Basavapathruni, Jodi Gureasko, Margaret Porter Scott, et al.Journal of the American Chemical Society|April 8, 2011
Direct detection of structurally resolved dynamics in a multiconformation receptor-ligand complexMary J Carroll, Anna V Gromova, Keith R Miller, et al.Pageof 6