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Biorxiv : the Preprint Server for Biology|June 9, 2020
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2Brandi N Williamson, Friederike Feldmann, Benjamin Schwarz, et al.Science Translational Medicine|December 30, 2021
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infectionMeghan S Vermillion, Eisuke Murakami, Bin Ma, et al.Antimicrobial Agents and Chemotherapy|February 21, 2024
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stabilityAndrew Mulato, Eric Lansdon, Ron Aoyama, et al.Antimicrobial Agents and Chemotherapy|June 27, 2026
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metaboliteYili Xu, Albert Liclican, Xiaofeng Zhao, et al.Nature|December 7, 2021
Long-acting capsid inhibitor protects macaques from repeat SHIV challengesSamuel J Vidal, Elena Bekerman, Derek Hansen, et al.Science (New York, N.Y.)|March 14, 2024
Oral administration of obeldesivir protects nonhuman primates against <i>Sudan ebolavirus</i>Robert W Cross, Courtney Woolsey, Victor C Chu, et al.Journal of Medicinal Chemistry|January 10, 2015
Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge studyRichard L Mackman, Michael Sangi, David Sperandio, et al.Science Translational Medicine|June 30, 2017
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronavirusesTimothy P Sheahan, Amy C Sims, Rachel L Graham, et al.Biorxiv : the Preprint Server for Biology|September 21, 2021
Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in miceAlexandra Schäfer, David R Martinez, John J Won, et al.Journal of Medicinal Chemistry|April 9, 2021
Prodrugs of a 1'-CN-4-Aza-7,9-dideazaadenosine <i>C</i>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSVRichard L Mackman, Hon C Hui, Michel Perron, et al.Pageof 14