Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Travis T Wager

Showing results (1-10 of 27) with videos related to

Pageof 3
Sort By:
ACS Medicinal Chemistry Letters|June 6, 2014
Getting the MAX out of Computational Models: The Prediction of Unbound-Brain and Unbound-Plasma Maximum ConcentrationsScot Mente, Angela Doran, Travis T Wager
ACS Chemical Neuroscience|March 19, 2016
Central Nervous System Multiparameter Optimization Desirability: Application in Drug DiscoveryTravis T Wager, Xinjun Hou, Patrick R Verhoest, et al.
Expert Opinion on Drug Metabolism & Toxicology|March 31, 2012
Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modelingTravis T Wager, Jennifer L Liras, Scot Mente, et al.
ACS Chemical Neuroscience|July 11, 2012
Moving beyond rules: the development of a central nervous system multiparameter optimization (CNS MPO) approach to enable alignment of druglike propertiesTravis T Wager, Xinjun Hou, Patrick R Verhoest, et al.
Expert Opinion on Drug Discovery|June 1, 2012
Strategies to optimize the brain availability of central nervous system drug candidatesTravis T Wager, Anabella Villalobos, Patrick R Verhoest, et al.
Journal of Medicinal Chemistry|May 27, 2016
Quantitative Assessment of the Impact of Fluorine Substitution on P-Glycoprotein (P-gp) Mediated Efflux, Permeability, Lipophilicity, and Metabolic StabilityMartin Pettersson, Xinjun Hou, Max Kuhn, et al.
ACS Chemical Neuroscience|July 11, 2012
Defining desirable central nervous system drug space through the alignment of molecular properties, in vitro ADME, and safety attributesTravis T Wager, Ramalakshmi Y Chandrasekaran, Xinjun Hou, et al.
Scientific Reports|July 22, 2016
Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesityPeter S Cunningham, Siobhán A Ahern, Laura C Smith, et al.
Current Biology : CB|March 25, 2014
A novel mechanism controlling resetting speed of the circadian clock to environmental stimuliVioletta Pilorz, Peter S Cunningham, Anthony Jackson, et al.
Journal of Medicinal Chemistry|November 14, 2013
Improving the odds of success in drug discovery: choosing the best compounds for in vivo toxicology studiesTravis T Wager, Bethany L Kormos, Joseph T Brady, et al.
Pageof 3

Showing results (1-10 of 27) with videos related to

Sort By:
Pageof 3
ACS Medicinal Chemistry Letters|June 6, 2014
Getting the MAX out of Computational Models: The Prediction of Unbound-Brain and Unbound-Plasma Maximum ConcentrationsScot Mente, Angela Doran, Travis T Wager
ACS Chemical Neuroscience|March 19, 2016
Central Nervous System Multiparameter Optimization Desirability: Application in Drug DiscoveryTravis T Wager, Xinjun Hou, Patrick R Verhoest, et al.
Expert Opinion on Drug Metabolism & Toxicology|March 31, 2012
Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modelingTravis T Wager, Jennifer L Liras, Scot Mente, et al.
ACS Chemical Neuroscience|July 11, 2012
Moving beyond rules: the development of a central nervous system multiparameter optimization (CNS MPO) approach to enable alignment of druglike propertiesTravis T Wager, Xinjun Hou, Patrick R Verhoest, et al.
Expert Opinion on Drug Discovery|June 1, 2012
Strategies to optimize the brain availability of central nervous system drug candidatesTravis T Wager, Anabella Villalobos, Patrick R Verhoest, et al.
Journal of Medicinal Chemistry|May 27, 2016
Quantitative Assessment of the Impact of Fluorine Substitution on P-Glycoprotein (P-gp) Mediated Efflux, Permeability, Lipophilicity, and Metabolic StabilityMartin Pettersson, Xinjun Hou, Max Kuhn, et al.
ACS Chemical Neuroscience|July 11, 2012
Defining desirable central nervous system drug space through the alignment of molecular properties, in vitro ADME, and safety attributesTravis T Wager, Ramalakshmi Y Chandrasekaran, Xinjun Hou, et al.
Scientific Reports|July 22, 2016
Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesityPeter S Cunningham, Siobhán A Ahern, Laura C Smith, et al.
Current Biology : CB|March 25, 2014
A novel mechanism controlling resetting speed of the circadian clock to environmental stimuliVioletta Pilorz, Peter S Cunningham, Anthony Jackson, et al.
Journal of Medicinal Chemistry|November 14, 2013
Improving the odds of success in drug discovery: choosing the best compounds for in vivo toxicology studiesTravis T Wager, Bethany L Kormos, Joseph T Brady, et al.
Pageof 3