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Showing results (81-90 of 91) with videos related to

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Bioorganic & Medicinal Chemistry Letters|February 15, 2011
Pyridyl amides as potent inhibitors of T-type calcium channelsThomas S Reger, Zhi-Qiang Yang, Kelly-Ann S Schlegel, et al.
Science Translational Medicine|April 5, 2013
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognitionJason M Uslaner, Spencer J Tye, Donnie M Eddins, et al.
Bioorganic & Medicinal Chemistry Letters|February 21, 2017
Investigation of orexin-2 selective receptor antagonists: Structural modifications resulting in dual orexin receptor antagonistsJason W Skudlarek, Christina N DiMarco, Kerim Babaoglu, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of 4,4-Disubstituted Quinazolin-2-ones as T-Type Calcium Channel AntagonistsJames C Barrow, Kenneth E Rittle, Thomas S Reger, et al.
Chemmedchem|December 31, 2013
Discovery of 5''-chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomniaAnthony J Roecker, Swati P Mercer, John D Schreier, et al.
Cell Biochemistry and Biophysics|July 8, 2009
Positive allosteric interaction of structurally diverse T-type calcium channel antagonistsVictor N Uebele, Cindy E Nuss, Steven V Fox, et al.
Chemmedchem|February 7, 2012
Discovery of [(2R,5R)-5-{[(5-fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): a dual orexin receptor antagonist with potent sleep-promoting propertiesPaul J Coleman, John D Schreier, Christopher D Cox, et al.
Bioorganic & Medicinal Chemistry Letters|September 25, 2014
Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomniaAnthony J Roecker, Thomas S Reger, M Christa Mattern, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Short-acting T-type calcium channel antagonists significantly modify sleep architecture in rodentsZhi-Qiang Yang, Kelly-Ann S Schlegel, Youheng Shu, et al.
Journal of Medicinal Chemistry|June 11, 2008
Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonistWilliam D Shipe, James C Barrow, Zhi-Qiang Yang, et al.
Pageof 10

Showing results (81-90 of 91) with videos related to

Sort By:
Pageof 10
Bioorganic & Medicinal Chemistry Letters|February 15, 2011
Pyridyl amides as potent inhibitors of T-type calcium channelsThomas S Reger, Zhi-Qiang Yang, Kelly-Ann S Schlegel, et al.
Science Translational Medicine|April 5, 2013
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognitionJason M Uslaner, Spencer J Tye, Donnie M Eddins, et al.
Bioorganic & Medicinal Chemistry Letters|February 21, 2017
Investigation of orexin-2 selective receptor antagonists: Structural modifications resulting in dual orexin receptor antagonistsJason W Skudlarek, Christina N DiMarco, Kerim Babaoglu, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of 4,4-Disubstituted Quinazolin-2-ones as T-Type Calcium Channel AntagonistsJames C Barrow, Kenneth E Rittle, Thomas S Reger, et al.
Chemmedchem|December 31, 2013
Discovery of 5''-chloro-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2':5',3''-terpyridine-3'-carboxamide (MK-1064): a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomniaAnthony J Roecker, Swati P Mercer, John D Schreier, et al.
Cell Biochemistry and Biophysics|July 8, 2009
Positive allosteric interaction of structurally diverse T-type calcium channel antagonistsVictor N Uebele, Cindy E Nuss, Steven V Fox, et al.
Chemmedchem|February 7, 2012
Discovery of [(2R,5R)-5-{[(5-fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): a dual orexin receptor antagonist with potent sleep-promoting propertiesPaul J Coleman, John D Schreier, Christopher D Cox, et al.
Bioorganic & Medicinal Chemistry Letters|September 25, 2014
Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomniaAnthony J Roecker, Thomas S Reger, M Christa Mattern, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Short-acting T-type calcium channel antagonists significantly modify sleep architecture in rodentsZhi-Qiang Yang, Kelly-Ann S Schlegel, Youheng Shu, et al.
Journal of Medicinal Chemistry|June 11, 2008
Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonistWilliam D Shipe, James C Barrow, Zhi-Qiang Yang, et al.
Pageof 10