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Progress in Molecular Biology and Translational Science|August 26, 2017
Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and DisinfectantsByron Caughey, Christina D Orru, Bradley R Groveman, et al.
The Journal of General Virology|December 15, 2015
Sensitive and specific detection of classical scrapie prions in the brains of goats by real-time quaking-induced conversionRohana P Dassanayake, Christina D Orrú, Andrew G Hughson, et al.
Acta Neuropathologica Communications|February 10, 2018
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuICBradley R Groveman, Christina D Orrù, Andrew G Hughson, et al.
FEBS Letters|September 30, 2025
Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tauAlessia Santambrogio, Sofia Lövestam, Michael A Metrick, et al.
Prion|February 23, 2018
Design, implementation, and interpretation of amplification studies for prion detectionNicholas J Haley, Jürgen A Richt, Kristen A Davenport, et al.
The New England Journal of Medicine|August 8, 2014
A test for Creutzfeldt-Jakob disease using nasal brushingsChristina D Orrú, Matilde Bongianni, Giovanni Tonoli, et al.
Plos Pathogens|November 7, 2022
Cryo-EM of prion strains from the same genotype of host identifies conformational determinantsForrest Hoyt, Parvez Alam, Efrosini Artikis, et al.
Plos Pathogens|September 15, 2017
Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregatesBradley R Groveman, Gregory J Raymond, Katrina J Campbell, et al.
Plos Pathogens|December 15, 2010
Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassaysJason M Wilham, Christina D Orrú, Richard A Bessen, et al.
Acta Neuropathologica Communications|June 22, 2022
Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body diseaseSara Hall, Christina D Orrù, Geidy E Serrano, et al.
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