Showing results (1-10 of 15) with videos related to

Sort By:
Pageof 2
Organic Letters|July 29, 2014
A practical synthesis of indoles via a Pd-catalyzed C-N ring formationRishi G Vaswani, Brian K Albrecht, James E Audia, et al.
The Journal of Biological Chemistry|February 1, 2021
Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activityJacob I Stuckey, Nico R Cantone, Alexandre Côté, et al.
ACS Medicinal Chemistry Letters|June 20, 2020
Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence TimeAvinash Khanna, Alexandre Côté, Shilpi Arora, et al.
Bioorganic & Medicinal Chemistry Letters|July 20, 2015
Discovery, design, and synthesis of indole-based EZH2 inhibitorsVictor S Gehling, Rishi G Vaswani, Christopher G Nasveschuk, et al.
ACS Medicinal Chemistry Letters|June 20, 2020
Design and Synthesis of Styrenylcyclopropylamine LSD1 InhibitorsVictor S Gehling, John P McGrath, Martin Duplessis, et al.
Bioorganic & Medicinal Chemistry Letters|August 2, 2016
Identification of potent, selective KDM5 inhibitorsVictor S Gehling, Steven F Bellon, Jean-Christophe Harmange, et al.
Bioorganic & Medicinal Chemistry Letters|July 14, 2016
Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studiesJun Liang, Birong Zhang, Sharada Labadie, et al.
Bioorganic & Medicinal Chemistry Letters|April 9, 2015
Development of methyl isoxazoleazepines as inhibitors of BETMichael C Hewitt, Yves Leblanc, Victor S Gehling, et al.
ACS Medicinal Chemistry Letters|March 18, 2016
Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET BromodomainsAlexander M Taylor, Rishi G Vaswani, Victor S Gehling, et al.
Bioorganic & Medicinal Chemistry Letters|May 18, 2017
From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitorsJun Liang, Sharada Labadie, Birong Zhang, et al.
Pageof 2