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W J Cooper

Showing results (11-20 of 24) with videos related to

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Journal of Medicinal Chemistry|December 12, 2018
Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth ApproachNick Barton, Máire Convery, Anthony W J Cooper, et al.
Journal of Medicinal Chemistry|July 19, 2016
Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory DiseaseAugustin Amour, Nick Barton, Anthony W J Cooper, et al.
Journal of Chemical Information and Modeling|September 30, 2010
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicityGeorge Papadatos, Muhammad Alkarouri, Valerie J Gillet, et al.
Journal of Medicinal Chemistry|September 21, 2020
A Turing Test for Molecular GeneratorsJacob T Bush, Peter Pogany, Stephen D Pickett, et al.
Journal of Medicinal Chemistry|May 10, 2013
Optimized chemical probes for REV-ERBαRyan P Trump, Stefano Bresciani, Anthony W J Cooper, et al.
Bioorganic & Medicinal Chemistry Letters|June 30, 2007
N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: indazoles as phenol isosteres with improved pharmacokineticsPaul Bamborough, Richard M Angell, Inder Bhamra, et al.
Bioorganic & Medicinal Chemistry Letters|February 7, 2009
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administrationChristopher J Lunniss, Anthony W J Cooper, Colin D Eldred, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 14, 2009
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptorKeith Biggadike, Randy K Bledsoe, Diane M Coe, et al.
Bioorganic & Medicinal Chemistry Letters|January 25, 2011
Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicityHawa Diallo, Davina C Angell, Heather A Barnett, et al.
Bioorganic & Medicinal Chemistry Letters|June 10, 2008
Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitorsJ Nicole Hamblin, Tony D R Angell, Stuart P Ballantine, et al.
Pageof 3

Showing results (11-20 of 24) with videos related to

Sort By:
Pageof 3
Journal of Medicinal Chemistry|December 12, 2018
Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth ApproachNick Barton, Máire Convery, Anthony W J Cooper, et al.
Journal of Medicinal Chemistry|July 19, 2016
Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory DiseaseAugustin Amour, Nick Barton, Anthony W J Cooper, et al.
Journal of Chemical Information and Modeling|September 30, 2010
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicityGeorge Papadatos, Muhammad Alkarouri, Valerie J Gillet, et al.
Journal of Medicinal Chemistry|September 21, 2020
A Turing Test for Molecular GeneratorsJacob T Bush, Peter Pogany, Stephen D Pickett, et al.
Journal of Medicinal Chemistry|May 10, 2013
Optimized chemical probes for REV-ERBαRyan P Trump, Stefano Bresciani, Anthony W J Cooper, et al.
Bioorganic & Medicinal Chemistry Letters|June 30, 2007
N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: indazoles as phenol isosteres with improved pharmacokineticsPaul Bamborough, Richard M Angell, Inder Bhamra, et al.
Bioorganic & Medicinal Chemistry Letters|February 7, 2009
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administrationChristopher J Lunniss, Anthony W J Cooper, Colin D Eldred, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 14, 2009
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptorKeith Biggadike, Randy K Bledsoe, Diane M Coe, et al.
Bioorganic & Medicinal Chemistry Letters|January 25, 2011
Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicityHawa Diallo, Davina C Angell, Heather A Barnett, et al.
Bioorganic & Medicinal Chemistry Letters|June 10, 2008
Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitorsJ Nicole Hamblin, Tony D R Angell, Stuart P Ballantine, et al.
Pageof 3